Original Investigation

Intracardiac vs Transesophageal Echocardiography in Atrial Fibrillation Ablation

JAMA Cardiology 10.1001/jamacardio.2025.3687

October 08, 2025 at 11:00 AM EDT

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Is intracardiac echocardiography (ICE) noninferior to transesophageal echocardiography (TEE) in preventing periprocedural thromboembolic events during atrial fibrillation (AF) ablation?In this multicenter randomized clinical trial of 1810 patients undergoing AF ablation, periprocedural thromboembolic events occurred in 4 of 906 patients in the ICE group (0.4%) and in 5 of 904 patients in the TEE group (0.6%), demonstrating noninferiority of ICE.ICE may serve as a noninferior alternative to TEE for thromboembolic prevention during AF ablation.

Corresponding Authors: Xu Liu, MD (drliuxu@126.com), and Xumin Hou, MD (hxmchest@126.com), Department of Cardiology, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, No. 241 W Huaihai Rd, Xuhui District, Shanghai 200030, China.

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