Subclinical Coronary Atherosclerosis and Retinal Optical Coherence Tomography Angiography

Can evaluation of retinal microvasculature by optical coherence tomography angiography (OCTA) serve as a diagnostic tool for detecting subclinical coronary atherosclerosis?In this clinic-based cross-sectional cohort study that included 1286 patients who underwent both coronary computed tomography angiography (CTA) and OCTA, coronary artery calcium score, presence of plaque, obstructive coronary artery disease (CAD), severe CAD, segment stenosis score, and segment involvement score were significantly associated with parafoveal vascular density (PFVD).Reduced retinal PFVD was associated with subclinical coronary atherosclerosis and, alongside cardiovascular risk factors, may help identify patients needing comprehensive coronary screening.

Corresponding Authors: Seung-Whan Lee, MD, PhD, Department of Cardiology (seungwlee@amc.seoul.kr), and Young Hee Yoon, MD, PhD, Department of Ophthalmology (yhyoon@amc.seoul.kr), Asan Medical Center, University of Ulsan College of Medicine, 88 Olympic-ro 43-gil, Songpa-gu, Seoul 138-736, South Korea.

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