Viewpoint

The 340B Drug Pricing Program at a Crossroads

JAMA 10.1001/jama.2026.6812

May 18, 2026 at 11:00 AM EDT

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This Viewpoint presents the history of the Health Resources & Services Administration (HRSA) 340B Drug Pricing Program and 340B Rebate Model Pilot Program, summarizes their controversies and limitations, and calls for action by Congress and HRSA to address these issues and strengthen support for safety-net hospitals and clinics.

Corresponding Author: Ameet Sarpatwari, PhD, JD, Harvard Pilgrim Health Care Institute LLC, 401 Park Dr, Ste 401 E, Boston, MA 02215 (asarpatwari@hsph.harvard.edu).

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