Predictors of Long-Term Outcomes in Hypertrophic Cardiomyopathy

What are the important historical, imaging, genetic, and blood biomarker predictors of risks in hypertrophic cardiomyopathy?In this prospective registry-based study of 2698 patients with hypertrophic cardiomyopathy, primary composite outcomes in hypertrophic cardiomyopathy were predicted by cardiac magnetic resonance (CMR) imaging measures of left ventricular (LV) structure including mass and scar extent, LV function, heart failure history, and N-terminal pro–B-type natriuretic peptide (NT-proBNP). Sudden cardiac death outcomes, including appropriately treated ventricular arrhythmias, were predicted by LV structure and function and NT-proBNP.These results provide prospective evidence for incorporating CMR and NT-proBNP in the evaluation of patients with hypertrophic cardiomyopathy.

Corresponding Author: Christopher M. Kramer, MD, University of Virginia Health, 1215 Lee St, Box 800158, Charlottesville, VA 22908 (ckramer@virginia.edu).

Link to the article in your story

We encourage you to link out to this article in your story using the link below. It includes an access token that will give free access to the article for your readers up to one year after publication. (The link will be live after the article publishes and embargo is lifted.)

Please see the article for additional information, including full author list, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

Need more information? Contact us.