Editor's Pick Original Investigation

Loberamisal for Acute Ischemic Stroke

JAMA 10.1001/jama.2026.16557

September 10, 2026 at 11:05 AM EDT

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Among patients with acute ischemic stroke treated within 48 hours of symptom onset, intravenous loberamisal, compared with placebo, resulted in a higher proportion of patients achieving full functional outcomes at 90 days. Further studies are needed to validate these findings and establish whether the benefits could extend to a broader patient population.

Meeting Information: This paper will be presented at the 29th National Conference on Neurology in Xi’an, China.

Related: This paper has an Editorial.

Corresponding Authors: Yongjun Wang, MD (yongjunwang@ncrcnd.org.cn), and Shuya Li, MD (shuyali85@163.com), Department of Neurology, Beijing Tiantan Hospital, No. 119 S Fourth Ring W Rd, Fengtai District, Beijing 100070, China.

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