Estimating Intervention Effects With Difference-in-Differences
JAMA 10.1001/jama.2026.12551July 16, 2026 at 11:00 AM EDT
This Guide to Statistics and Methods provides an overview of the difference-in-differences method, a tool for addressing potential biases by contrasting the change in the outcome of interest from before an intervention to after, between settings experiencing and those not experiencing the intervention.
Link to the article in your story
We encourage you to link out to this article in your your story using the link below. It includes an access token that will give free access to the article for your readers up to one year after publication. (The link will be live after the article publishes and embargo is lifted.)
Please see the article for additional information, including full author list, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
Need more information? Contact us.