Viewpoint

Real-World Evidence for Medicare Drug Price Negotiations

JAMA 10.1001/jama.2025.21498

December 04, 2025 at 11:00 AM EST

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This Viewpoint discusses how real-world evidence studies could help the US Centers for Medicare & Medicaid Services align spending with value in their drug price negotiations.

Corresponding Author: Colleen Carey, PhD, Brooks School of Public Policy and Department of Economics, Cornell University, 2224 Martha van Rensselaer Hall, Ithaca, NY 14853 (colleen.carey@cornell.edu).

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