Special Communication

AI, Health, and Health Care Today and Tomorrow

JAMA 10.1001/jama.2025.18490

October 13, 2025 at 11:05 AM EDT

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AI will disrupt every part of health and health care delivery in the coming years. Given the many long-standing problems in health care, this disruption represents an incredible opportunity. However, the odds that this disruption will improve health for all will depend heavily on the creation of an ecosystem capable of rapid, efficient, robust, and generalizable knowledge about the consequences of these tools on health.

Corresponding Author: Derek C. Angus, MD, MPH, Critical Care Medicine, UPMC, 3550 Terrace St, 614 Scaife Hall, Pittsburgh, PA 15261 (angusdc@upmc.edu).

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