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JAMA Guide to Statistics and Methods

Pattern-Mixture Models for Missing Data

JAMA 10.1001/jama.2025.18109

October 30, 2025 at 11:00 AM EDT

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This JAMA Guide to Statistics and Methods article discusses designing and implementing clinical trials to minimize the number of missing data.

Corresponding Author: Roderick J. Little, PhD, Department of Biostatistics, University of Michigan, 1415 Washington Heights, Ann Arbor, MI 48109-2029 (rlittle@umich.edu).

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