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The FG Phase—A Biomolecular Condensate That Governs Transport Through Nuclear Pores

JAMA 10.1001/jama.2025.16179

September 11, 2025 at 9:00 AM EDT

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In this Viewpoint, 2025 Albert Lasker Basic Medical Research Award winner Dirk Görlich describes discoveries that exposed the structures and functions of protein sequences of low complexity, revealing new principles of intracellular transport, pathogenesis, and cellular organization.

Corresponding Author: Dirk Görlich, Dr rer nat, Max Planck Institute for Multidisciplinary Sciences, Am Fassberg 11, D-37077 Göttingen, Germany (goerlich@mpinat.mpg.de).

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