Research Letter

Initial Antibiotic Selection Strategy and Subsequent Antibiotic Use—Insights From the INSPIRE Trials

JAMA 10.1001/jama.2025.11256

July 17, 2025 at 11:00 AM EDT

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This study evaluates whether initial reductions in in-hospital extended-spectrum antibiotics are sustained during hospitalization.

Corresponding Author: Shruti K. Gohil, MD, MPH, Division of Infectious Diseases, University of California, Irvine School of Medicine, 100 Theory, Ste 120, Irvine, CA 92617 (skgohil@hs.uci.edu).

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