For The Media – JAMA Network

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, APRIL 23, 2013 Media Advisory: To contact Martin J. London. M.D., call Kristen Bole at 415-476-2743 or email kristen.bole@ucsf.edu. CHICAGO – Patients at elevated cardiac risk who were treated with beta-blockers on the day of or following noncardiac, nonvascular surgery had significantly lower rates of 30-day mortality and…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, APRIL 23, 2013 Media Advisory: To contact corresponding author Monique V. Chireau, M.D. M.P.H., call Rachel Harrison at 919-419-5069 or email rachel.harrison@duke.edu.  CHICAGO – For women with abdominal pain or vaginal bleeding during early pregnancy, patient history and clinical examination alone are insufficient to indicate or eliminate the…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, APRIL 23, 2013 Media Advisory: To contact Casper Roed, M.D., email casperroed@hotmail.com or call 011-45-404-33438. CHICAGO – In a study that included nearly 3,000 adults from Denmark, a diagnosis of meningococcal, pneumococcal, or Haemophilus influenzae meningitis in childhood was associated with lower educational achievement and economic self-sufficiency in…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, APRIL 23, 2013 Media Advisory: To contact Jakob Christensen, Ph.D., email jakob@farm.au.dk. To contact editorial co-author Kimford J. Meador, M.D., call Holly Korschun at 404-727-3990 or email hkorsch@emory.edu. CHICAGO – Maternal use of valproate (a drug used for the treatment of epilepsy and other neuropsychological disorders) during pregnancy…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, APRIL 16, 2013 Electrocardiographic Abnormality Associated With Increased Risk of Atrial Fibrillation, Congestive Heart Failure “Left anterior fascicular block (LAFB) is considered a benign electrocardiographic (ECG) finding, but its long-term consequences have not been comprehensively studied,” writes Mala C. Mandyam, B.S., of the University of California, San Francisco…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, APRIL 16, 2013 Media Advisory: To contact corresponding author Andreas M. Zeiher, M.D., email zeiher@em.uni-frankfurt.de. CHICAGO – Treatment that consisted of shock wave (procedure using high-dose ultrasound)-mediated preconditioning of the target heart tissue prior to administration of bone marrow-derived mononuclear cells was associated with significant, albeit modest improvement…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, APRIL 16, 2013 Media Advisory: To contact corresponding author Luigi Titomanlio, M.D., Ph.D., email luigi.titomanlio@rdb.aphp.fr. To contact editorial co-author Leon G. Epstein, M.D., call Marla Paul at 312-503-8928 or email marla-paul@northwestern.edu. CHICAGO – In a study including children and adolescents 6 to 18 years of age, those who…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, APRIL 16, 2013 Media Advisory: To contact corresponding author Atul A. Gawande, M.D., M.P.H., call Marjorie Dwyer at 617-432-8416 or email mhdwyer@hsph.harvard.edu. To contact editorial author Uwe E. Reinhardt, Ph.D., call Elisabeth Donahue at 609-258-5988 or email edonahue@Princeton.edu. CHICAGO – Findings of an analysis that included nearly 35,000…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, APRIL 16, 2013 Media Advisory: To contact Koon Teo, M.B., Ph.D., call Susan Emigh at 905-525-9140, ext. 22555 or email emighs@mcmaster.ca. CHICAGO – Among patients with a coronary heart disease or stroke event from countries with varying income levels, the prevalence of healthy lifestyle behaviors (such as regular…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, APRIL 9, 2013 New Approaches to Molecular Diagnosis “Advances in understanding the molecular basis of rare and common disorders, as well as in the technology of DNA analysis, are rapidly changing the landscape of molecular genetic and genomic testing,” writes Bruce R. Korf, M.D., Ph.D., of the University…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, APRIL 9, 2013 Media Advisory: To contact Mingzhao Xing, M.D., Ph.D., call Vanessa Wasta at 410-614-2916 or email wasta@jhmi.edu. To contact editorial co-author Anne R. Cappola, M.D., Sc.M., call Kim Menard at 215-662-6183 or email kim.menard@uphs.upenn.edu. CHICAGO – Presence of the genetic mutation BRAF V600E was significantly associated…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, APRIL 9, 2013 Media Advisory: To contact corresponding author Michael J. Ackerman, M.D., Ph.D., call Traci Klein at 507-284-5005 or email klein.traci@mayo.edu. To contact editorial co-author Alan E. Guttmacher, M.D., call Robert Bock at 301-496-5133 or email bockr@mail.nih.gov. CHICAGO – In a molecular genetic evaluation involving 91 cases…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, APRIL 9, 2013 Media Advisory: To contact corresponding author Richard Mayeux, M.D., M.Sc., call Elizabeth Streich at 212-305-3689 or email estreich@columbia.edu. To contact editorial author Robert L. Nussbaum, M.D., call Kristen Bole at 415-476-2743 or email kristen.bole@ucsf.edu. CHICAGO – In a meta-analysis of data from nearly 6,000 African…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, APRIL 9, 2013 Media Advisory: To contact corresponding author Mark J. Pallen, M.A., M.D., Ph.D., email m.pallen@warwick.ac.uk. To contact editorial author David A. Relman, M.D., call Margarita Gallardo at 650-723-7897 or email mjgallardo@stanford.edu. CHICAGO – Researchers have been able to reconstruct the genome sequence of an outbreak strain…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, APRIL 2, 2013 The Inevitable Application of Big Data to Health Care “The amount of data being digitally collected and stored is vast and expanding rapidly. As a result, the science of data management and analysis is also advancing to enable organizations to convert this vast resource into…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, APRIL 2, 2013 Media Advisory: To contact Vance G. Fowler Jr., M.D., M.H.S., call Sarah Avery at 919-660-1306 or email sarah.avery@duke.edu. To contact editorial author Preeti N. Malani, M.D., M.S.J., call Beata Mostafavi at 734-764-2220 or email bmostafa@med.umich.edu. CHICAGO – Use of a vaccine to prevent Staphylococcus aureus…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, APRIL 2, 2013 Media Advisory: To contact Ciaran J. McMullan, M.D., call Tom Langford at 617-534-1605 or email tlangford@partners.org. CHICAGO – With previous evidence suggesting that melatonin may have a role in glucose metabolism, researchers have found an independent association between decreased secretion of melatonin and an increased…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, APRIL 2, 2013 Media Advisory: To contact Karen E. Joynt, M.D., M.P.H., call Todd Datz at 617-432-8413 or email tdatz@hsph.harvard.edu. To contact editorial author John P. A. Ioannidis, M.D., D.Sc., call Margarita Gallardo at 650-723-7897 or email mjgallardo@stanford.edu. CHICAGO – In an analysis that included data on more…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, APRIL 2, 2013 Media Advisory: To contact Ellen M. Lavoie Smith, Ph.D., call Nicole Fawcett at 734-764-2220 or email nfawcett@umich.edu; or call Mary Beth Lewis at 734-763-1682 or email lewismb@umich.edu. CHICAGO –Among patients with painful chemotherapy-induced peripheral neuropathy, use of the anti-depressant drug duloxetine for 5 weeks re­sulted…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, MARCH 26, 2013 Media Advisory: To contact Josje Altenburg, M.D., email j.altenburg@mca.nl. To contact David J. Serisier, M.B.B.S., D.M., F.R.A.C.P., email david.serisier@mater.org.au. To contact editorial co-author J. Stuart Elborn, M.D., email s.elborn@qub.ac.uk. CHICAGO – Among patients with the lung disorder non-cystic fibrosis bronchiectasis, treatment with the antibiotic azithromycin…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, MARCH 26, 2013 The Economics of Genomic Medicine – Insights From the IOM Roundtable on Translating Genomic-Based Research for Health In this Viewpoint, W. Gregory Feero, M.D., Ph.D., of the Maine-Dartmouth Family Medicine Residency, Augusta, Maine (Dr. Feero is also Contributing Editor, JAMA), and colleagues discuss several of…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, MARCH 26, 2013 Media Advisory: To contact Sandra Y. Lin, M.D., call David March at 410-955-1534 or email dmarch1@jhmi.edu. To contact editorial author Harold S. Nelson, M.D., call Adam Dormuth at 303-398-1082 or email DormuthA@NJHealth.org. CHICAGO – In an examination of a type of treatment for allergic rhinitis…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, MARCH 26, 2013 Media Advisory: To contact Gervasio A. Lamas, M.D., call Joanna Palmer at 305-674-2589 or email Jpalmer2@msmc.com. To contact editorial co-author Howard Bauchner, M.D., call Jann Ingmire at 312-464-2499 or email jann.ingmire@jamanetwork.org. To contact editorial author Steven E. Nissen, M.D., call Wyatt DuBois at 216-445-9946 or…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, MARCH 19, 2013 Health Services Innovation – The Time is Now “Biomedical innovation has improved prevention, diagnosis, and treatment resulting in reduction in mortality for most diseases. However, health and health care disparities remain across the life-span because these advances have not been matched by advances in delivering…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, MARCH 19, 2013 Media Advisory: To contact Steven M. Opal, M.D., call David Orenstein at 401-863-1862 or email david_orenstein@brown.edu. CHICAGO – Administration of the drug eritoran to patients with severe sepsis and septic shock failed to demonstrate a significant effect on reducing all-cause 28-day mortality or 1-year mortality,…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, MARCH 19, 2013 Media Advisory: To contact corresponding author Frank-Erik de Leeuw, M.D., Ph.D., email H.deLeeuw@neuro.umcn.nl. To contact editorial author Graeme J. Hankey, M.D., F.R.C.P., F.R.C.P. Edin., F.R.A.C.P., email graeme.hankey@uwa.edu.au. CHICAGO – In an examination of long-term mortality after stroke, adults 50 years of age and younger who…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, MARCH 19, 2013 Media Advisory: To contact Maria C. Raven, M.D., M.P.H., M.Sc., call Elizabeth Fernandez at 415-514-1592 or email efernandez@pubaff.ucsf.edu. To contact editorial author James G. Adams, M.D., call Erin White at 847-491-4888 or email ewhite@northwestern.edu. CHICAGO – Among patients with emergency department (ED) visits with the…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, MARCH 12, 2013 Teaching Physicians to Care Amid Chaos Allan S. Detsky, M.D., Ph.D., of the University of Toronto, and Donald M. Berwick, M.D., of Harvard Medical School, Boston, examine the changes that have taken place in patient care in recent decades. “In 2013, inpatient medical care in…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, MARCH 12, 2013 Media Advisory: To contact Adnan K. Chhatriwalla, M.D., call Kerry A. O’Connor at 816-932-8646 or email koconnor@saint-lukes.org. CHICAGO – In a study that included 3.3 million percutaneous coronary intervention (PCI; procedures such as balloon angioplasty or stent placement used to open narrowed coronary arteries) procedures,…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, MARCH 12, 2013 Media Advisory: To contact co-author R. Doug McEvoy, M.D., email doug.mcevoy@health.sa.gov.au. CHICAGO – Among patients who were identified as likely having moderate to severe obstructive sleep apnea, treatment based in primary care was not clinically inferior to treatment at a specialist sleep center for improvement…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, MARCH 12, 2013 Media Advisory: To contact Richard M. Martin, Ph.D., email richard.martin@bristol.ac.uk. CHICAGO – In research that included nearly 14,000 healthy infants in Belarus, an intervention that succeeded in improving the duration and exclusivity of breastfeeding during infancy did not result in a lower risk of overweight…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, MARCH 12, 2013 Media Advisory: To contact corresponding author Carole Clair, M.D., M.Sc., email carole.willi@gmail.com. To contact co-author James B. Meigs, M.D., M.P.H., call Ryan Donovan at 617-724-6433 or email rcdonovan@partners.org. To contact editorial co-author Michael C. Fiore, M.D., M.P.H., M.B.A., call Christopher Hollenback at 608-262-3902 or email…

EMBARGOED FOR EARLY RELEASE: 1:15 P.M. (CT) MONDAY, MARCH 11, 2013 Media Advisory: To contact Mihai Gheorghiade, M.D., call Erin White at 847-491-4888 or email ewhite@northwestern.edu. CHICAGO – Among patients hospitalized for heart failure (HF) with reduced left ventricular ejection fraction (LVEF; a measure of how well the left ventricle of the heart pumps with…

EMBARGOED FOR EARLY RELEASE: 1:30 P.M. (CT) MONDAY, MARCH 11, 2013 Media Advisory: To contact Margaret M. Redfield, M.D., call Traci Klein at 507-990-1182 or email klein.traci@mayo.edu. CHICAGO – Among patients with heart failure with preserved ejection fraction (a measure of heart function), administration of sildenafil for 24 weeks, compared with placebo, did not result…

EMBARGOED FOR EARLY RELEASE: 10 A.M. (CT) THURSDAY, MARCH 7, 2013 Media Advisory: To contact Jared M. O’Leary, M.D., call Jessica Maki at 617-534-1603 or email jmaki3@partners.org. CHICAGO – Jared M. O’Leary, M.D., of Brigham and Women’s Hospital, Boston, and colleagues analyzed U.S. hospitalizations from 1998 through 2010 for children and adults with congenital heart…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, MARCH 5, 2013 Index May Help Predict 10-Year Mortality Among Older Adults “Recent guidelines recommend considering patients’ life expectancy when deciding whether to pursue preventive interventions with long lag times to benefit (≥ 7 years) such as colorectal cancer screening and intensive glycemic control for diabetes. However, most…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, MARCH 5, 2013 Media Advisory: To contact corresponding author Raymond J. Kim, M.D., call Sarah Avery at 919-660-1306 or email sarah.avery@duke.edu. To contact editorial co-author Marc A. Pfeffer, M.D., Ph.D., call Jessica Maki at 617-534-1603 or email jmaki3@partners.org. CHICAGO – Among patients with coronary artery disease referred for…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, MARCH 5, 2013 Media Advisory: To contact corresponding author Sanjay K. Prasad, M.D., email s.prasad@rbht.nhs.uk. CHICAGO – Detection of midwall fibrosis (the presence of scar tissue in the middle of the heart muscle wall) via magnetic resonance imaging among patients with nonischemic dilated cardiomyopathy (a condition affecting the…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, MARCH 5, 2013 Media Advisory: To contact Kevin L. Winthrop, M.D., M.P.H., call Mirabai Vogt at 503-494-7986 or email vogtmi@ohsu.edu. CHICAGO – Although patients with rheumatoid arthritis (RA) have a disproportionately higher incidence of herpes zoster (shingles), an analysis that included nearly 60,000 patients with RA and other…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, FEBRUARY 26, 2013 Why the Ethics of Parsimonious Medicine Is Not the Ethics of Rationing In this Viewpoint, Jon C. Tilburt, M.D., of the Mayo Clinic, Rochester, Minn., and Christine K. Cassel, M.D., of the American Board of Internal Medicine, Philadelphia, discuss the ethical differences between parsimonious medicine…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, FEBRUARY 26, 2013 Media Advisory: To contact corresponding author Burkert Pieske, M.D., email burkert.pieske@medunigraz.at. To contact editorial co-author John G. F. Cleland, M.D., Ph.D., F.R.C.P., email J.G.Cleland@hull.ac.uk. CHICAGO – Among patients with heart failure with preserved ejection fraction, long-term treatment with the medication spironolactone improved left ventricular diastolic…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, FEBRUARY 26, 2013 Media Advisory: To contact Simon G. Thompson, D.Sc., email sgt27@medschl.cam.ac.uk. CHICAGO – In contrast to the commonly adopted surveillance intervals in current abdominal aortic aneurysm (AAA) screening programs, surveillance intervals of several years may be clinically acceptable for the majority of patients with small AAA,…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, FEBRUARY 26, 2013 Media Advisory: To contact Justin B. Dimick, M.D., M.P.H., call Shantell Kirkendoll at 734-764-2220 or email smkirk@umich.edu. To contact Caprice C. Greenberg, M.D., M.P.H., call Susan Lampert Smith at 608-890-5643 or email SSmith5@uwhealth.org. CHICAGO – In an analysis of data on patients who underwent bariatric…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, FEBRUARY 26, 2013 Media Advisory: To contact Rebecca H. Johnson, M.D., call Alyse Bernal at 206-987-5213 or email alyse.bernal@seattlechildrens.org. CHICAGO – An analysis of breast cancer trends in the U.S. finds a small but statistically significant increase in the incidence of advanced breast cancer for women 25 to…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, FEBRUARY 19, 2013 Opioid Analgesics Involved in Most Pharmaceutical Overdose Deaths “Data recently released by the National Center for Health Statistics show drug overdose deaths increased for the 11th consecutive year in 2010. Pharmaceuticals, especially opioid analgesics, have driven this increase. Other pharmaceuticals are involved in opioid overdose…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, FEBRUARY 19, 2013 Media Advisory: To contact Sheldon Cohen, Ph.D., call Shilo Rea at 412-268-6094 or email shilo@cmu.edu. CHICAGO – Among healthy adults who were administered a cold virus, those with shorter telomere length (a structure at the end of a chromosome) in certain cells were more likely…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, FEBRUARY 19, 2013 Media Advisory: To contact Ryan Zarychanski, M.D., M.Sc., call Ilana Simon at 204-789-3427 or email ilana.simon@med.umanitoba.ca. To contact editorial author Massimo Antonelli, M.D., email m.antonelli@rm.unicatt.it. CHICAGO – In an analysis of studies that examined critically ill patients requiring an increase in blood fluid volume, intravenous…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, FEBRUARY 19, 2013 Media Advisory: To contact Jason D. Wright, M.D., call the Columbia University Medical Center Office of Communications at 212-305-3900 or email cumcnews@columbia.edu. To contact editorial co-author Joel S. Weissman, Ph.D., call Lori Schroth at 617-534-1604 or email ljschroth@partners.org. CHICAGO –Between 2007 and 2010, the use…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, FEBRUARY 12, 2013 Improving Access to Mental Health Services for Youth in the United States “In the wake of the recent school shooting in Newtown, Connecticut, a public dialogue emerged about the accessibility of mental health care in the United States. Policy makers have called for a more…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, FEBRUARY 12, 2013 Media Advisory: To contact corresponding author Feiko O. ter Kuile, Ph.D., email terkuile@liv.ac.uk. CHICAGO – Among pregnant women in sub-Saharan Africa, intermittent preventive therapy for malaria with 3 or more doses of the drug regimen sulfadoxine-pyrimethamine was associated with a higher birth weight and lower…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, FEBRUARY 12, 2013 Media Advisory: To contact Harlan M. Krumholz, M.D., S.M., call Karen Peart at 203-432-1326 or email karen.peart@yale.edu. CHICAGO – In a study that included data on nearly 3 million hospital admissions for Medicare beneficiaries with heart attack, pneumonia or heart failure, researchers failed to find…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, FEBRUARY 12, 2013 Media Advisory: To contact Philippe Prokocimer, M.D., call Laura Kempke or Andrew Law at 781-684-0770 or email trius@mslgroup.com. To contact editorial co-author Helen W. Boucher, M.D., call Julie Jette at 617-636-3265 or email jjette@tuftsmedicalcenter.org. CHICAGO – Treatment with a newer antibiotic, tedizolid phosphate, once daily…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, FEBRUARY 12, 2013 Media Advisory: To contact Douglas R. Morgan, M.D., M.P.H., call Craig Boerner at 615- 322-4747 or email craig.boerner@vanderbilt.edu. CHICAGO – In an analysis of the results of interventions to eradicate the bacterium Helicobacter pylori (a risk factor for gastric cancer) in seven diverse community populations…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, FEBRUARY 12, 2013 Media Advisory: To contact Pal Surén, M.D., M.P.H., email pal.suren@fhi.no. To contact editorial co-author Robert J. Berry, M.D., M.P.H.T.M., call CDC Media Relations at 404-639-3286 or email media@cdc.gov. CHICAGO – In a study that included approximately 85,000 Norwegian children, maternal use of supplemental folic acid…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, FEBRUARY 5, 2013 Study Examines Rate of Antipsychotic Use Among Nursing Home Residents “The prescribing of antipsychotic medications persists at high levels in U.S. nursing homes (NHs) despite extensive data demonstrating marginal clinical benefits and serious adverse effects, including death. However, imprecise and outdated data have limited the…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, FEBRUARY 5, 2013 Media Advisory: To contact corresponding author Bill Vicenzino, Ph.D., email b.vicenzino@uq.edu.au. CHICAGO – Among patients with chronic unilateral lateral epicondylalgia (“tennis elbow”), a single injection of corticosteroid medication was associated with poorer outcomes after one year and higher recurrence rates compared with placebo, while eight…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, FEBRUARY 5, 2013 Media Advisory: To contact Anna A. Ahimastos, Ph.D., email A.Ahimastos@alfred.org.au. To contact editorial author Mary McGrae McDermott, M.D., call Marla Paul at 312-503-8928 or email marla-paul@northwestern.edu. CHICAGO – Among patients with peripheral artery disease and intermittent claudication (pain in the calf that comes and goes,…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, FEBRUARY 5, 2013 Media Advisory: To contact Joan M. Teno, M.D., M.S., call David Orenstein at 401-863-1862 or email david_orenstein@brown.edu. To contact editorial co-author Mary E. Tinetti, M.D., call Karen Peart at 203-432-1326 or email karen.peart@yale.edu. CHICAGO – In a study that included data on more than 800,000…

EMBARGOED FOR EARLY RELEASE: 12:55 P.M. (CT) TUESDAY, JANUARY 22, 2013 Media Advisory: To contact Amal Jubran, M.D., call Maureen Dyman at 708-202-5627 or email Maureen.Dyman@va.gov. CHICAGO – Among patients with a tracheostomy requiring prolonged mechanical ventilation and treated at a single long-term care facility, unassisted breathing using an oxygen delivery device connected to a…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JANUARY 22, 2013 Study Identifies What Type of Hospitals are More Likely to Receive Penalties For Failing to Reduce Hospital Readmissions “The federal Hospital Readmissions Reduction Program (HRRP) took effect on October 1, 2012, the first day of fiscal year 2013. Under this program, using claims data from…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JANUARY 22, 2013 Media Advisory: To contact corresponding author Harlan M. Krumholz, M.D., S.M., call Karen Peart at 203-432-1326 or email karen.peart@yale.edu. CHICAGO – Among approximately 3 million Medicare patients hospitalized for heart failure, heart attack, or pneumonia, readmissions were frequent throughout the 30 days following the hospitalization,…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JANUARY 22, 2013 Media Advisory: To contact corresponding author Joanne Lynn, M.D., M.A., M.S., call Ken Schwartz at 571-733-5709 or email Ken.Schwartz@altarum.org. To contact editorial author Mark V. Williams, M.D., call Marla Paul at 312-503-8928 or email marla-paul@northwestern.edu. CHICAGO – Communities in which quality improvement initiatives for care…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JANUARY 22, 2013 Media Advisory: To contact Jay G. Berry, M.D., M.P.H., call Meghan Weber at 617-919-3110 or email meghan.weber@childrens.harvard.edu. To contact editorial co-author Rajendu Srivastava, M.D., F.R.C.P.C., M.P.H., call Phil Sahm at 801-581-2517 or email phil.sahm@hsc.utah.edu. CHICAGO – In a national sample of 72 children’s hospitals, 6.5…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JANUARY 22, 2013 Media Advisory: To contact Anita A. Vashi, M.D., M.P.H., call Karen Peart at 203-432-1326 or email karen.peart@yale.edu. CHICAGO – In a study that included more than 4 million patients, nearly 20 percent of hospitalizations resulted in at least 1 acute care encounter within the 30…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JANUARY 15, 2013 Mega-Trials for Blockbusters John P. A. Ioannidis, M.D., D.Sc., of the Stanford University School of Medicine, Stanford, Calif., writes that mega-trials (very large, simple trials) should be conducted for licensed interventions with annual sales that exceed $1 billion, i.e., a blockbuster. These blockbusters “should have…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JANUARY 15, 2013 Media Advisory: To contact Jean Reignier, M.D., Ph.D., email jean.reignier@chd-vendee.fr. To contact editorial author Todd W. Rice, M.D., M.Sc., call Craig Boerner at 615-322-4747 or email craig.boerner@vanderbilt.edu. CHICAGO – Patients undergoing mechanical ventilation and receiving nutrition via a feeding tube who did not receive monitoring…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JANUARY 15, 2013 Media Advisory: To contact corresponding author William H. Shrank, M.D., M.S.H.S., call Brian Cook or Isabella Leung of the CMS Press Office at 202-690-6145 or email press@cms.hhs.gov. To contact editorial author Jack Hoadley, Ph.D., call Lauren Mullins at 202-687-2269 or email lm973@georgetown.edu. CHICAGO – In…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JANUARY 15, 2013 Media Advisory: To contact Kohei Hasegawa, M.D., M.P.H., call Kristen Stanton at 617-643-3907 or email kstanton3@partners.org. To contact editorial co-author Donald M. Yealy, M.D., call Rick Pietzak at 412-864-4151 or email pietzakr@upmc.edu. CHICAGO – In patients with out-of-hospital cardiac arrest, cardiopulmonary resuscitation with advanced airway…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JANUARY 8, 2013 How to Decide Whether a Clinical Practice Guideline Is Trustworthy David F. Ransohoff, M.D., of the University of North Carolina School of Medicine, Chapel Hill, and colleagues discuss concerns about the process of developing clinical practice guidelines and the standards for developing practice guidelines created…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JANUARY 8, 2013 Media Advisory: To contact co-author Dick Tibboel, M.D., Ph.D., email d.tibboel@erasmusmc.nl. To contact editorial author Kanwaljeet J. S. Anand, M.B.B.S., D.Phil., F.R.C.P.C.H., call Sheila Champlin at 901-448-4957 or email schampli@uthsc.edu. CHICAGO – Among infants undergoing major surgery, postoperative use of intermittent intravenous paracetamol (acetaminophen) for…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JANUARY 8, 2013 Media Advisory: To contact Vanessa G. Allen, M.D., M.P.H., call Nicole Helsberg at 647-260-7466 or email nicole.helsberg@oahpp.ca. To contact editorial author Robert D. Kirkcaldy, M.D., M.P.H., call the NCHHSTP Media Office at 404-639-8895 or email NCHHSTPMediaTeam@cdc.gov. CHICAGO – In an examination of the effectiveness of…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JANUARY 8, 2013 Media Advisory: To contact Timothy McAlindon, D.M., M.P.H., call Julie Jette at 617-636-3265 or email jjette@tuftsmedicalcenter.org. CHICAGO – In a two year randomized trial, patients with symptomatic knee osteoarthritis who received vitamin D supplementation did not have a significant difference in knee pain or cartilage…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JANUARY 1, 2013 How and Why U.S. Health Care Differs From That in Other OECD Countries Victor R. Fuchs, Ph.D., of Stanford University, Stanford, Calif., compares U.S. health care to that in other countries of the Organization for Economic Co-operation and Development (OECD), and “reaches one inescapable conclusion—U.S….

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JANUARY 1, 2013 Media Advisory: To contact Carolien Roos, M.D., email c.roos@obgyn.umcn.nl. CHICAGO – In women with threatened (symptoms of) preterm labor, maintenance therapy to suppress labor with the calcium-channel blocker nifedipine for 12 days did not result in a significant reduction in adverse perinatal (just before and…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JANUARY 1, 2013 Media Advisory: To contact Sana M. Al-Khatib, M.D., M.H.S., call Sarah Avery at 919-660-1306 or email sarah.avery@duke.edu. CHICAGO – Comparing the largest registry of implantable cardioverter-defibrillator (ICD) implants in the United States with 2 primary prevention randomized clinical trials, researchers found that patients who met…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JANUARY 1, 2013 Media Advisory: To contact Olof Stephansson, M.D., Ph.D., email olof.stephansson@ki.se. CHICAGO – In a study that included nearly 30,000 women from Nordic countries who had filled a selective serotonin reuptake inhibitor (SSRI) prescription during pregnancy, researchers found no significant association between use of these medications…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JANUARY 1, 2013 Media Advisory: To contact corresponding author Robert S. Sherwin, M.D., call Helen Dodson at 303-436-3984 or email helen.dodson@yale.edu. To contact editorial co-author Jonathan Q. Purnell, M.D., call Mirabai Vogt at 503-494-7986 or email vogtmi@ohsu.edu. CHICAGO – In a study examining possible factors regarding the associations…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JANUARY 1, 2013 Media Advisory: To contact Katherine M. Flegal, Ph.D., call Karen Hunter at 404-639-3286 or email ksh7@cdc.gov. To contact editorial co-author Steven B. Heymsfield, M.D., email Steven.heymsfield@pbrc.edu. CHICAGO – In an analysis of nearly 100 studies that included approximately 3 million adults, relative to normal weight,…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, DECEMBER 25, 2012 Obesity May Be Declining Among Preschool-Aged Children Living in Low-Income Families “Obesity and extreme obesity in childhood, which are more prevalent among minority and low-income families, have been associated with other cardiovascular risk factors, increased health care costs, and premature death. Obesity and extreme obesity…