EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, MARCH 5, 2013 Media Advisory: To contact corresponding author Sanjay K. Prasad, M.D., email s.prasad@rbht.nhs.uk. CHICAGO – Detection of midwall fibrosis (the presence of scar tissue in the middle of the heart muscle wall) via magnetic resonance imaging among patients with nonischemic dilated cardiomyopathy (a condition affecting the…
Use of Certain Therapies For Inflammatory Diseases Does Not Appear to Increase Risk of Shingles
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, MARCH 5, 2013 Media Advisory: To contact Kevin L. Winthrop, M.D., M.P.H., call Mirabai Vogt at 503-494-7986 or email vogtmi@ohsu.edu. CHICAGO – Although patients with rheumatoid arthritis (RA) have a disproportionately higher incidence of herpes zoster (shingles), an analysis that included nearly 60,000 patients with RA and other…
JAMA:02262013
Viewpoints in This Issue of JAMA
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, FEBRUARY 26, 2013 Why the Ethics of Parsimonious Medicine Is Not the Ethics of Rationing In this Viewpoint, Jon C. Tilburt, M.D., of the Mayo Clinic, Rochester, Minn., and Christine K. Cassel, M.D., of the American Board of Internal Medicine, Philadelphia, discuss the ethical differences between parsimonious medicine…
Long-Term Use of Medication May Improve Heart Function, But Does Not Improve Symptoms, Quality of Life for Heart Failure Patients
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, FEBRUARY 26, 2013 Media Advisory: To contact corresponding author Burkert Pieske, M.D., email burkert.pieske@medunigraz.at. To contact editorial co-author John G. F. Cleland, M.D., Ph.D., F.R.C.P., email J.G.Cleland@hull.ac.uk. CHICAGO – Among patients with heart failure with preserved ejection fraction, long-term treatment with the medication spironolactone improved left ventricular diastolic…
Findings Suggest That Number and Frequency of Surveillance Scans For Small Abdominal Aortic Aneurysms Can Be Reduced For Most Patients
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, FEBRUARY 26, 2013 Media Advisory: To contact Simon G. Thompson, D.Sc., email sgt27@medschl.cam.ac.uk. CHICAGO – In contrast to the commonly adopted surveillance intervals in current abdominal aortic aneurysm (AAA) screening programs, surveillance intervals of several years may be clinically acceptable for the majority of patients with small AAA,…
No Significant Difference Seen in Bariatric Surgery Complications Rates Following Restricting Coverage to Higher-Quality Centers
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, FEBRUARY 26, 2013 Media Advisory: To contact Justin B. Dimick, M.D., M.P.H., call Shantell Kirkendoll at 734-764-2220 or email smkirk@umich.edu. To contact Caprice C. Greenberg, M.D., M.P.H., call Susan Lampert Smith at 608-890-5643 or email SSmith5@uwhealth.org. CHICAGO – In an analysis of data on patients who underwent bariatric…
Study Finds Small Increase in Incidence of Advanced Breast Cancer Among Younger Women
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, FEBRUARY 26, 2013 Media Advisory: To contact Rebecca H. Johnson, M.D., call Alyse Bernal at 206-987-5213 or email alyse.bernal@seattlechildrens.org. CHICAGO – An analysis of breast cancer trends in the U.S. finds a small but statistically significant increase in the incidence of advanced breast cancer for women 25 to…
JAMA:02192013
Also Appearing in This Issue of JAMA
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, FEBRUARY 19, 2013 Opioid Analgesics Involved in Most Pharmaceutical Overdose Deaths “Data recently released by the National Center for Health Statistics show drug overdose deaths increased for the 11th consecutive year in 2010. Pharmaceuticals, especially opioid analgesics, have driven this increase. Other pharmaceuticals are involved in opioid overdose…
Association Found Between Length of Biological Marker and Development of Respiratory Infection in Healthy Adults
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, FEBRUARY 19, 2013 Media Advisory: To contact Sheldon Cohen, Ph.D., call Shilo Rea at 412-268-6094 or email shilo@cmu.edu. CHICAGO – Among healthy adults who were administered a cold virus, those with shorter telomere length (a structure at the end of a chromosome) in certain cells were more likely…
Intravenous Fluid Used to Increase Blood Volume in Critically Ill Patients Associated With Increased Risk of Death, Kidney Injury
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, FEBRUARY 19, 2013 Media Advisory: To contact Ryan Zarychanski, M.D., M.Sc., call Ilana Simon at 204-789-3427 or email ilana.simon@med.umanitoba.ca. To contact editorial author Massimo Antonelli, M.D., email m.antonelli@rm.unicatt.it. CHICAGO – In an analysis of studies that examined critically ill patients requiring an increase in blood fluid volume, intravenous…
Increase Seen in Use Of Robotically-Assisted Hysterectomy For Benign Gynecologic Disorders
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, FEBRUARY 19, 2013 Media Advisory: To contact Jason D. Wright, M.D., call the Columbia University Medical Center Office of Communications at 212-305-3900 or email cumcnews@columbia.edu. To contact editorial co-author Joel S. Weissman, Ph.D., call Lori Schroth at 617-534-1604 or email ljschroth@partners.org. CHICAGO –Between 2007 and 2010, the use…
JAMA:02122013
Viewpoints in This Issue of JAMA
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, FEBRUARY 12, 2013 Improving Access to Mental Health Services for Youth in the United States “In the wake of the recent school shooting in Newtown, Connecticut, a public dialogue emerged about the accessibility of mental health care in the United States. Policy makers have called for a more…
Higher Number of Doses of Malaria Preventive Therapy During Pregnancy Associated With Better Outcomes for Infants in Africa
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, FEBRUARY 12, 2013 Media Advisory: To contact corresponding author Feiko O. ter Kuile, Ph.D., email terkuile@liv.ac.uk. CHICAGO – Among pregnant women in sub-Saharan Africa, intermittent preventive therapy for malaria with 3 or more doses of the drug regimen sulfadoxine-pyrimethamine was associated with a higher birth weight and lower…
No Strong Association Found Between Hospital Readmission and Mortality Rates For Medicare Patients Admitted for Heart Attack, Pneumonia, Heart Failure
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, FEBRUARY 12, 2013 Media Advisory: To contact Harlan M. Krumholz, M.D., S.M., call Karen Peart at 203-432-1326 or email karen.peart@yale.edu. CHICAGO – In a study that included data on nearly 3 million hospital admissions for Medicare beneficiaries with heart attack, pneumonia or heart failure, researchers failed to find…
Newer, Shorter-Course Antibiotic Shows Similar Effectiveness For Treating Skin Infection
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, FEBRUARY 12, 2013 Media Advisory: To contact Philippe Prokocimer, M.D., call Laura Kempke or Andrew Law at 781-684-0770 or email trius@mslgroup.com. To contact editorial co-author Helen W. Boucher, M.D., call Julie Jette at 617-636-3265 or email jjette@tuftsmedicalcenter.org. CHICAGO – Treatment with a newer antibiotic, tedizolid phosphate, once daily…
Study Identifies Factors Associated With Eradication of Bacteria Linked to Gastric Cancer
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, FEBRUARY 12, 2013 Media Advisory: To contact Douglas R. Morgan, M.D., M.P.H., call Craig Boerner at 615- 322-4747 or email craig.boerner@vanderbilt.edu. CHICAGO – In an analysis of the results of interventions to eradicate the bacterium Helicobacter pylori (a risk factor for gastric cancer) in seven diverse community populations…
Prenatal Folic Acid Supplementation Associated With Lower Risk of Autism
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, FEBRUARY 12, 2013 Media Advisory: To contact Pal Surén, M.D., M.P.H., email pal.suren@fhi.no. To contact editorial co-author Robert J. Berry, M.D., M.P.H.T.M., call CDC Media Relations at 404-639-3286 or email media@cdc.gov. CHICAGO – In a study that included approximately 85,000 Norwegian children, maternal use of supplemental folic acid…
JAMA:02052013
Also Appearing in This Issue of JAMA
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, FEBRUARY 5, 2013 Study Examines Rate of Antipsychotic Use Among Nursing Home Residents “The prescribing of antipsychotic medications persists at high levels in U.S. nursing homes (NHs) despite extensive data demonstrating marginal clinical benefits and serious adverse effects, including death. However, imprecise and outdated data have limited the…
Corticosteroid Injection, Physiotherapy Do Not Provide Significant Improvement for ‘Tennis Elbow’
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, FEBRUARY 5, 2013 Media Advisory: To contact corresponding author Bill Vicenzino, Ph.D., email b.vicenzino@uq.edu.au. CHICAGO – Among patients with chronic unilateral lateral epicondylalgia (“tennis elbow”), a single injection of corticosteroid medication was associated with poorer outcomes after one year and higher recurrence rates compared with placebo, while eight…
Use of ACE Inhibitor by Patients With Peripheral Artery Disease May Improve Pain-Free Walking, Physical Functioning
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, FEBRUARY 5, 2013 Media Advisory: To contact Anna A. Ahimastos, Ph.D., email A.Ahimastos@alfred.org.au. To contact editorial author Mary McGrae McDermott, M.D., call Marla Paul at 312-503-8928 or email marla-paul@northwestern.edu. CHICAGO – Among patients with peripheral artery disease and intermittent claudication (pain in the calf that comes and goes,…
Lower Proportion of Medicare Patients Dying in Hospitals; Increase Seen in Use of ICUs in Last Month of Life
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, FEBRUARY 5, 2013 Media Advisory: To contact Joan M. Teno, M.D., M.S., call David Orenstein at 401-863-1862 or email david_orenstein@brown.edu. To contact editorial co-author Mary E. Tinetti, M.D., call Karen Peart at 203-432-1326 or email karen.peart@yale.edu. CHICAGO – In a study that included data on more than 800,000…
JAMA_OF:01222013
Study Evaluates Approaches for Weaning Patients With Tracheostomy From Long-Term Ventilator Support
EMBARGOED FOR EARLY RELEASE: 12:55 P.M. (CT) TUESDAY, JANUARY 22, 2013 Media Advisory: To contact Amal Jubran, M.D., call Maureen Dyman at 708-202-5627 or email Maureen.Dyman@va.gov. CHICAGO – Among patients with a tracheostomy requiring prolonged mechanical ventilation and treated at a single long-term care facility, unassisted breathing using an oxygen delivery device connected to a…
JAMA:01222013
Also Appearing in This Issue of JAMA
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JANUARY 22, 2013 Study Identifies What Type of Hospitals are More Likely to Receive Penalties For Failing to Reduce Hospital Readmissions “The federal Hospital Readmissions Reduction Program (HRRP) took effect on October 1, 2012, the first day of fiscal year 2013. Under this program, using claims data from…
Hospital Readmission for Older Patients Often For Different Illness
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JANUARY 22, 2013 Media Advisory: To contact corresponding author Harlan M. Krumholz, M.D., S.M., call Karen Peart at 203-432-1326 or email karen.peart@yale.edu. CHICAGO – Among approximately 3 million Medicare patients hospitalized for heart failure, heart attack, or pneumonia, readmissions were frequent throughout the 30 days following the hospitalization,…
Study Evaluates Rehospitalizations and Hospitalizations For Medicare Beneficiaries Following Implementation of Quality Improvement Intervention for Care Transition
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JANUARY 22, 2013 Media Advisory: To contact corresponding author Joanne Lynn, M.D., M.A., M.S., call Ken Schwartz at 571-733-5709 or email Ken.Schwartz@altarum.org. To contact editorial author Mark V. Williams, M.D., call Marla Paul at 312-503-8928 or email marla-paul@northwestern.edu. CHICAGO – Communities in which quality improvement initiatives for care…
Research Finds Substantial Variation in Readmission Rate Among Children’s Hospitals
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JANUARY 22, 2013 Media Advisory: To contact Jay G. Berry, M.D., M.P.H., call Meghan Weber at 617-919-3110 or email meghan.weber@childrens.harvard.edu. To contact editorial co-author Rajendu Srivastava, M.D., F.R.C.P.C., M.P.H., call Phil Sahm at 801-581-2517 or email phil.sahm@hsc.utah.edu. CHICAGO – In a national sample of 72 children’s hospitals, 6.5…
Emergency Department Use Within 30 Days of Hospital Discharge Common
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JANUARY 22, 2013 Media Advisory: To contact Anita A. Vashi, M.D., M.P.H., call Karen Peart at 203-432-1326 or email karen.peart@yale.edu. CHICAGO – In a study that included more than 4 million patients, nearly 20 percent of hospitalizations resulted in at least 1 acute care encounter within the 30…
JAMA:01152013
Viewpoints in This Issue of JAMA
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JANUARY 15, 2013 Mega-Trials for Blockbusters John P. A. Ioannidis, M.D., D.Sc., of the Stanford University School of Medicine, Stanford, Calif., writes that mega-trials (very large, simple trials) should be conducted for licensed interventions with annual sales that exceed $1 billion, i.e., a blockbuster. These blockbusters “should have…
Absence of Monitoring of Stomach Fluid Volume for Patients on Ventilator and Feeding Tube Does Not Increase Risk of Pneumonia; May Improve Feeding
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JANUARY 15, 2013 Media Advisory: To contact Jean Reignier, M.D., Ph.D., email jean.reignier@chd-vendee.fr. To contact editorial author Todd W. Rice, M.D., M.Sc., call Craig Boerner at 615-322-4747 or email craig.boerner@vanderbilt.edu. CHICAGO – Patients undergoing mechanical ventilation and receiving nutrition via a feeding tube who did not receive monitoring…
Higher Quality Rating For Medicare Advantage Plan Associated With Increased Likelihood of Plan Enrollment
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JANUARY 15, 2013 Media Advisory: To contact corresponding author William H. Shrank, M.D., M.S.H.S., call Brian Cook or Isabella Leung of the CMS Press Office at 202-690-6145 or email press@cms.hhs.gov. To contact editorial author Jack Hoadley, Ph.D., call Lauren Mullins at 202-687-2269 or email lm973@georgetown.edu. CHICAGO – In…
Advanced Airway Procedures for Out-of-Hospital Cardiac Arrest Associated With Poorer Neurological Outcomes
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JANUARY 15, 2013 Media Advisory: To contact Kohei Hasegawa, M.D., M.P.H., call Kristen Stanton at 617-643-3907 or email kstanton3@partners.org. To contact editorial co-author Donald M. Yealy, M.D., call Rick Pietzak at 412-864-4151 or email pietzakr@upmc.edu. CHICAGO – In patients with out-of-hospital cardiac arrest, cardiopulmonary resuscitation with advanced airway…
JAMA:01082013
Viewpoints in This Issue of JAMA
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JANUARY 8, 2013 How to Decide Whether a Clinical Practice Guideline Is Trustworthy David F. Ransohoff, M.D., of the University of North Carolina School of Medicine, Chapel Hill, and colleagues discuss concerns about the process of developing clinical practice guidelines and the standards for developing practice guidelines created…
Post-Operative Intravenous Acetaminophen May Help Reduce Use of Morphine In Infants
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JANUARY 8, 2013 Media Advisory: To contact co-author Dick Tibboel, M.D., Ph.D., email d.tibboel@erasmusmc.nl. To contact editorial author Kanwaljeet J. S. Anand, M.B.B.S., D.Phil., F.R.C.P.C.H., call Sheila Champlin at 901-448-4957 or email schampli@uthsc.edu. CHICAGO – Among infants undergoing major surgery, postoperative use of intermittent intravenous paracetamol (acetaminophen) for…
Study Documents Failure Rate of Antibiotic Treatment for Gonorrhea
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JANUARY 8, 2013 Media Advisory: To contact Vanessa G. Allen, M.D., M.P.H., call Nicole Helsberg at 647-260-7466 or email nicole.helsberg@oahpp.ca. To contact editorial author Robert D. Kirkcaldy, M.D., M.P.H., call the NCHHSTP Media Office at 404-639-8895 or email NCHHSTPMediaTeam@cdc.gov. CHICAGO – In an examination of the effectiveness of…
Vitamin D Supplementation Does Not Reduce Knee Pain, Cartilage Loss in Patients With Osteoarthritis
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JANUARY 8, 2013 Media Advisory: To contact Timothy McAlindon, D.M., M.P.H., call Julie Jette at 617-636-3265 or email jjette@tuftsmedicalcenter.org. CHICAGO – In a two year randomized trial, patients with symptomatic knee osteoarthritis who received vitamin D supplementation did not have a significant difference in knee pain or cartilage…
JAMA:01012013
Viewpoints in This Week’s JAMA
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JANUARY 1, 2013 How and Why U.S. Health Care Differs From That in Other OECD Countries Victor R. Fuchs, Ph.D., of Stanford University, Stanford, Calif., compares U.S. health care to that in other countries of the Organization for Economic Co-operation and Development (OECD), and “reaches one inescapable conclusion—U.S….
Maintenance Therapy With Calcium-Channel Blocker to Suppress Premature Labor Does Not Significantly Reduce Adverse Perinatal Outcomes
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JANUARY 1, 2013 Media Advisory: To contact Carolien Roos, M.D., email c.roos@obgyn.umcn.nl. CHICAGO – In women with threatened (symptoms of) preterm labor, maintenance therapy to suppress labor with the calcium-channel blocker nifedipine for 12 days did not result in a significant reduction in adverse perinatal (just before and…
Study Finds No Significant Difference in Survival Between Patients Who Receive ICDs in Clinical Practice vs. Clinical Trials
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JANUARY 1, 2013 Media Advisory: To contact Sana M. Al-Khatib, M.D., M.H.S., call Sarah Avery at 919-660-1306 or email sarah.avery@duke.edu. CHICAGO – Comparing the largest registry of implantable cardioverter-defibrillator (ICD) implants in the United States with 2 primary prevention randomized clinical trials, researchers found that patients who met…
Use of Anti-Depressants During Pregnancy Not Associated With Increased Risk of Stillbirth, Infant Death
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JANUARY 1, 2013 Media Advisory: To contact Olof Stephansson, M.D., Ph.D., email olof.stephansson@ki.se. CHICAGO – In a study that included nearly 30,000 women from Nordic countries who had filled a selective serotonin reuptake inhibitor (SSRI) prescription during pregnancy, researchers found no significant association between use of these medications…
Imaging Study Examines Effect of Fructose on Brain Regions That Regulate Appetite
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JANUARY 1, 2013 Media Advisory: To contact corresponding author Robert S. Sherwin, M.D., call Helen Dodson at 303-436-3984 or email helen.dodson@yale.edu. To contact editorial co-author Jonathan Q. Purnell, M.D., call Mirabai Vogt at 503-494-7986 or email vogtmi@ohsu.edu. CHICAGO – In a study examining possible factors regarding the associations…
Higher Levels of Obesity Associated With Increased Risk of Death; Being Overweight Associated With Lower Risk of Death
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JANUARY 1, 2013 Media Advisory: To contact Katherine M. Flegal, Ph.D., call Karen Hunter at 404-639-3286 or email ksh7@cdc.gov. To contact editorial co-author Steven B. Heymsfield, M.D., email Steven.heymsfield@pbrc.edu. CHICAGO – In an analysis of nearly 100 studies that included approximately 3 million adults, relative to normal weight,…
JAMA_OF:12212012
JAMA:12252012
Also Appearing in This Issue of JAMA
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, DECEMBER 25, 2012 Obesity May Be Declining Among Preschool-Aged Children Living in Low-Income Families “Obesity and extreme obesity in childhood, which are more prevalent among minority and low-income families, have been associated with other cardiovascular risk factors, increased health care costs, and premature death. Obesity and extreme obesity…
Sustained Virological Response Associated With Improved Survival For Certain Patients With Chronic Hepatitis C Virus Infection
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, DECEMBER 25, 2012 Media Advisory: To contact corresponding author Harry L. A. Janssen, M.D., Ph.D., email h.janssen@erasmusmc.nl. CHICAGO – Among patients with chronic hepatitis C virus infection and advanced hepatic fibrosis (development of excess fibrous connective tissue), sustained virological response (SVR) to interferon-based treatment was associated with a…
Autopsy-Based Study Examines Prevalence of Atherosclerosis Among U.S. Service Members
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, DECEMBER 25, 2012 Media Advisory: To contact Bryant J. Webber, M.D., call Sharon Willis at 301-295-3578 or email sharon.willis@usuhs.edu. To contact editorial author Daniel Levy, M.D., call the NHLBI press office at 301-496-4236 or email nhlbi_news@nhlbi.nih.gov. CHICAGO – Among deployed U.S. service members who died of combat or…
JAMA:12182012
Viewpoints in This Week’s JAMA
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, DECEMBER 18, 2012 Iodine Supplementation During Pregnancy and Lactation Alex Stagnaro-Green, M.D., M.H.P.E., of the George Washington University School of Medicine and Health Sciences, Washington, D.C., and colleagues discuss the possible adverse effects of iodine deficiency and the importance of supplementation during pregnancy and while breastfeeding. “The status…
Administration of Clopidogrel Prior to PCI Associated With Reduction in Major Cardiac Events, But Not Improved Survival
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, DECEMBER 18, 2012 Media Advisory: To contact corresponding author Gilles Montalescot, M.D., Ph.D., email gilles.montalescot@psl.aphp.fr. CHICAGO – Among patients scheduled for a percutaneous coronary intervention (PCI; procedures such as balloon angioplasty or stent placement used to open narrowed coronary arteries), pretreatment with the antiplatelet agent clopidogrel was not…
Intensive Weight-Loss Intervention Associated With Increased Likelihood of Partial Remission From Diabetes, Although Improvement in Rate Modest
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, DECEMBER 18, 2012 Media Advisory: To contact Edward W. Gregg, Ph.D., call Karen Hunter at 404-639-3286 or email ksh7@cdc.gov. To contact editorial co-author David E. Arterburn, M.D., M.P.H., call Joan DeClaire at 206-287-2653 or email declaire.j@ghc.org. CHICAGO – Among overweight adults, participation in an intensive lifestyle intervention (that…
Regular Aspirin Use 10 or More Years Ago Associated With Increased Risk of Type of Age-Related Macular Degeneration
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, DECEMBER 18, 2012 Media Advisory: To contact Barbara E. K. Klein, M.D., M.P.H., call Susan Lampert Smith at 608-262-7335 or email slsmith2@wisc.edu. CHICAGO – Among nearly 5,000 study participants, regular aspirin use reported ten years prior was associated with a small but statistically significant increase in the risk…
World Trade Center Rescue and Recovery Workers Have Had Increased Incidence of Certain Types of Cancer
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, DECEMBER 18, 2012 Media Advisory: To contact co-author Steven D. Stellman, Ph.D., M.P.H., call Jean Weinberg at 347-396-4177 or email jweinberg@health.nyc.gov; or Marcus Liem at 347-396-2919 or email mliem@health.nyc.gov. CHICAGO – Among rescue and recovery workers exposed to the dust, debris, and fumes following the World Trade Center…
JAMA:12112012
Also Appearing in This Issue of JAMA
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, DECEMBER 11, 2012 Study Finds Association Between Weight of Pancreas and Potential Diabetes Biomarker Autopsy and imaging studies suggest that among adults with type 1 diabetes (T1D), their pancreas is smaller and weighs less than the pancreas of adults without the disease. However, it is unknown when pancreatic…
Combination Therapy May Help Decrease Sleep Apnea Symptoms at Higher Altitudes
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, DECEMBER 11, 2012 Media Advisory: To contact corresponding author Konrad E. Bloch, M.D., email konrad.bloch@usz.ch. CHICAGO – For individuals with obstructive sleep apnea traveling to higher altitudes (which may exacerbate symptoms), use of a combination therapy resulted in improvement in symptoms including reduced insomnia and better control of…
Prevalence of Visual Impairment in U.S. Increases
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, DECEMBER 11, 2012 Media Advisory: To contact corresponding author David S. Friedman, M.D., M.P.H., Ph.D., call John Lazarou at 410-502-8902 or email jlazaro1@jhmi.edu. To contact editorial co-author David C. Musch, Ph.D., M.P.H., call Betsy Nisbet at 734-647-5586 or email bsnisbet@umich.edu. CHICAGO – The prevalence of nonrefractive visual impairment…
JAMA:12042012
Viewpoints in This Week’s JAMA
Embargoed for Release: 3 p.m. CT Tuesday, December 4, 2012 Overcoming the Obstacles to Research During Residency – What Does It Take? Michael B. Rothberg, M.D., M.P.H., of the Cleveland Clinic, writes that “although most physicians work as clinicians and never perform research, the Accreditation Council for Graduate Medical Education requires that residents ‘participate in…
Study Examines Attitudes of Medical Students’ Toward Industry Following COI Disclosures by Preclinical Lecturers
Embargoed for Release: 3 p.m. CT Tuesday, December 4, 2012 Media Advisory: To contact corresponding author Deborah Korenstein, M.D., call Kevin Orozovich at 212-241-9200 or email newsmedia@mssm.edu. Azalea Kim, M.P.A., of the Mount Sinai School of Medicine, New York, and colleagues studied the association between routine conflicts of interest (COI) disclosure with preclinical medical students…
Bias May Exist in Rating of Medical Trainees
Embargoed for Release: 3 p.m. CT Tuesday, December 4, 2012 Media Advisory: To contact Peter Yeates, M.B.B.S., M.Clin.Ed., email peter.yeates@manchester.ac.uk. Peter Yeates, M.B.B.S., M.Clin.Ed., of the University of Manchester, United Kingdom, and colleagues conducted a study to examine whether observations of the performance of postgraduate year 1 physicians influence raters’ scores of subsequent performances. “The…
Research Evaluates Possible Benefit of Multiple Mini-Interviews as Part of Medical School Admission Process
Embargoed for Release: 3 p.m. CT Tuesday, December 4, 2012 Media Advisory: To contact Kevin W. Eva, Ph.D., call Brian Kladko at 604-827-3301 or email brian.kladko@ubc.ca. Kevin W. Eva, Ph.D., of the University of British Columbia, Vancouver, and colleagues conducted a study to determine whether students deemed acceptable through a revised admissions protocol using a…
Clinically Integrated E-Learning of Evidence-Based Medicine Improves Knowledge, Skills in Resource-Limited Countries
Embargoed for Release: 3 p.m. CT Tuesday, December 4, 2012 Media Advisory: To contact corresponding author Khalid S. Khan, M.B.B.S., M.Sc., email k.s.khan@qmul.ac.uk. Regina Kulier, M.D., of the World Health Organization, Geneva, Switzerland, and colleagues conducted a study to evaluate the effects of a clinically integrated e-learning evidence-based medicine (EBM) course on knowledge, skills, and…
Shorter Rotation for Attending Physicians Does Not Appear to Have Adverse Effects on Patients; May Decrease Physician Burnout
Embargoed for Release: 3 p.m. CT Tuesday, December 4, 2012 Media Advisory: To contact Brian P. Lucas, M.D., M.S., call Nancy Di Fiore at 312-942-5159 or email Nancy_DiFiore@rush.edu. Brian P. Lucas, M.D., M.S., of the Cook County Health and Hospitals System and Rush Medical College, Chicago, and colleagues conducted a study to compare the effects…
Program of Protected Time For Sleep Improves Morning Alertness For Medical Interns
Embargoed for Release: 3 p.m. CT Tuesday, December 4, 2012 Media Advisory: To contact Kevin G. Volpp, M.D., Ph.D., call Jessica Mikulski at 215-349-8369 or email jessica.mikulski@uphs.upenn.edu Kevin G. Volpp, M.D., Ph.D., of the Philadelphia Veterans Affairs Medical Center and University of Pennsylvania, Philadelphia, and colleagues conducted a study to determine whether a protected sleep…
Low Percentage of Medical Residents Plan to Practice General Internal Medicine
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, DECEMBER 4, 2012 Media Advisory: To contact Colin P. West, M.D., Ph.D., call Alyson Fleming at 507-284-5005 or email newsbureau@mayo.edu. Colin P. West, M.D., Ph.D., and Denise M. Dupras, M.D., Ph.D., of Mayo Clinic, Rochester, Minn., conducted a study to evaluate career plans of internal medicine residents. “General…
JAMA:11272012
Also Appearing in This Week’s JAMA
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, NOVEMBER 27, 2012 Earnings of U.S. Physicians Grow Less Than Other Health Professionals “Understanding trends in physician earnings is important given health care cost growth and proposed Medicare physician fee reductions,” writes Seth A. Seabury, Ph.D., of the RAND Corporation, Santa Monica, Calif., and colleagues. National surveys…
Anticoagulation Treatment For Longer Than Three Months After Aortic Valve Replacement Associated With Decreased Risk of Cardiovascular Death
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, NOVEMBER 27, 2012 Media Advisory: To contact Charlotte Merie, M.D., email c.merie@mail.dk. To contact editorial co-author Shamir R. Mehta, M.D., M.Sc., call Veronica McGuire at 905-525-9140, ext. 22169, or email vmcguir@mcmaster.ca. CHICAGO – Although current guidelines recommend 3 months of anticoagulation treatment after bioprosthetic aortic valve replacement surgery,…
Risk of Pertussis Increases as Time Since Last Dose of DTaP Vaccine Lengthens
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, NOVEMBER 27, 2012 Media Advisory: To contact Lara K. Misegades, Ph.D., M.S., call Alison Patti at 404-639-3286 or email APatti@cdc.gov. To contact editorial co-author Eugene D. Shapiro, M.D., call Karen Peart at 203-432-1326 or email karen.peart@yale.edu. CHICAGO – In an examination of cases of childhood pertussis in California,…
Studies Examine Whether Therapies for Heart Failure Are Associated With Improved Survival
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, NOVEMBER 27, 2012 Media Advisory: To contact Adrian F. Hernandez, M.D., M.H.S., call Sarah Avery at 919-660-1306 or email sarah.avery@duke.edu. To contact Lars H. Lund, M.D., Ph.D., email lars.lund@alumni.duke.edu. To contact editorial author James C. Fang, M.D., call Mike Ferrari at 216-844-7239 or email Mike.Ferrari@uhhospitals.org. CHICAGO – An…
JAMA:11202012
Also Appearing in This Week’s JAMA
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, NOVEMBER 20, 2012 Study Finds That Older Persons With Positive Age Stereotypes More Likely to Recover From Severe Disability “Little research has been conducted on factors that account for why some older persons recover from disability and others do not. We considered a new culture-based explanatory factor: age…
Citicoline Does Not Improve Functional, Cognitive Status in Patients with Traumatic Brain Injury
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, NOVEMBER 20, 2012 Media Advisory: To contact Ross D. Zafonte, D.O., call Tim Sullivan at 617-573-2918 or email tsullivan11@partners.org. To contact editorial co-author Robert L. Ruff, M.D., Ph.D., call Jessica Studeny at 216-368-4692 or email jessica.studeny@case.edu. CHICAGO – Although approved for use for treating traumatic brain injury (TBI)…
Patients With Online Access to Clinicians, Medical Records Have Increased Use of Clinical Services
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, NOVEMBER 20, 2012 Media Advisory: To contact Ted E. Palen, M.D., Ph.D., M.S.P.H., call Amy Whited at 303-344-7518 or email Amy.L.Whited@kp.org. To contact editorial co-author David W. Bates, M.D., M.Sc., call Lori Schroth at 617-534-1604 or email Ljshanks@partners.org. CHICAGO – Patients with online access to their medical records…
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Also Appearing in This Week’s JAMA
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, NOVEMBER 13, 2012 Study Examines Brain White Matter Changes in Soccer Players “Soccer is the most popular sport in the world, with more than 250 million active players. It is the only sport in which the unprotected head is a primary point of contact when heading the ball….
Genetic Variation May Modify Associations Between Low Vitamin D Levels and Adverse Health Outcomes
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, NOVEMBER 13, 2012 Media Advisory: To contact Gregory P. Levin, Ph.D., call Leila Gray at 206-685-0381 or email leilag@u.washington.edu. CHICAGO – Findings from a study suggest that certain variations in vitamin D metabolism genes may modify the association of low serum 25-hydroxyvitamin D concentrations with health outcomes such…
Having Migraines Associated With Higher Incidence of Brain Lesions Among Women; Effect on Health Uncertain
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, NOVEMBER 13, 2012 Media Advisory: To contact corresponding author Mark C. Kruit, M.D., Ph.D., email m.c.kruit@lumc.nl. To contact editorial co-author Deborah I. Friedman, M.D., M.P.H., call Jeff Carlton at 214-648-2876 or email Jeffrey.Carlton@utsouthwestern.edu. CHICAGO – After nearly 10 years of follow-up of study participants who experienced migraines and…
Patients With HBV-Related Liver Cancer Who Receive Antiviral Therapy Have Lower Risk of Tumor Recurrence
EMBARGOED FOR EARLY RELEASE: 2:45 P.M. (CT) MONDAY, NOVEMBER 12, 2012 Media Advisory: To contact Chun-Ying Wu, M.D., Ph.D., M.P.H., email chun@vghtc.gov.tw. To contact editorial author Anna S. F. Lok, M.D., call Nicole Fawcett at 734-764-2220 or email nfawcett@umich.edu. CHICAGO – Patients with hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC; liver cancer) who received nucleoside…
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Study Examines Effect of Timing of Cell Therapy Following Heart Attack
FOR RELEASE: 2 P.M. (CT) MONDAY, NOVEMBER 5, 2012 Jay H. Traverse, M.D., of the Minneapolis Heart Institute at Abbott Northwestern Hospital, Minneapolis, and colleagues investigated the influence of timing of cardiovascular cell delivery within the first week after a heart attack on improving left ventricular (LV) function following reperfusion. “Cell therapy may eventually become…
Study Evaluates Mesenchymal Stem Cell Therapies for Cardiac Patients
FOR RELEASE: 2 P.M. (CT) MONDAY, NOVEMBER 5, 2012 Joshua M. Hare, M.D., of the University of Miami Miller School of Medicine, and colleagues conducted a study to examine whether allogeneic (taken from a different individual) mesenchymal stem cells (MSCs) are as safe and effective as autologous (donor and recipient are the same person) MSCs…
Patients Who Cannot Tolerate Statins Achieve Reduction in LDL Cholesterol Levels With Administration of Monoclonal Antibody
EMBARGOED FOR EARLY RELEASE: 12:45 P.M. (CT) MONDAY, NOVEMBER 5, 2012 David Sullivan, M.D., of the Royal Prince Alfred Hospital, Camperdown, Australia, and colleagues conducted a phase 2 study to assess the efficacy and safety of subcutaneous (under the skin) administration of a human monoclonal antibody to the protein PCSK9, (the product is designated AMG145),…
Comparison of Anti-Clotting Drugs Finds Differences in Platelet Reactivity, Similar Clinical Outcomes
EMBARGOED FOR EARLY RELEASE: 5:30 P.M. (CT) SUNDAY, NOVEMBER 4, 2012 Paul A. Gurbel, M.D., of the Sinai Center for Thrombosis Research, Baltimore, and colleagues conducted a study to examine the differences in platelet reactivity and clinical outcomes among patients with acute coronary syndromes (ACS) being treated by the antiplatelet agents clopidogrel or prasugrel. From…
Pre-Operative and Post-Operative Fish Oil Supplementation Does Not Appear Effective in Reducing Atrial Fibrillation Following Heart Surgery
EMBARGOED FOR EARLY RELEASE: 11 A.M. (CT) MONDAY, NOVEMBER 5, 2012 Media Advisory: To contact corresponding author Dariush Mozaffarian, M.D., Dr.P.H., call Todd Datz at 617-432-8413 or email tdatz@hsph.harvard.edu. To contact corresponding author Roberto Marchioli, M.D., email marchioli@negrisud.it. CHICAGO – Among patients undergoing cardiac surgery, supplementation with a n-3-polyunsaturated fatty acid (fish oil) before…