JAMANEU:10132014

JAMANEU_OF:10132014

Dysregulation in Orexinergic System Associated with Alzheimer Disease

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, OCTOBER 13, 2014 Media Advisory: To contact author Claudio Liguori, M.D., email dott.claudioliguori@yahoo.it. To contact editorial author Luigi Ferini-Strambi, M.D., email ferinistrambi.luigi@hsr.it. To place an electronic embedded link in your story Links for this study and editorial will be live at the embargo time: http://archneur.jamanetwork.com/article.aspx?doi=10.1001/jamaneurol.2014.2510 and http://archneur.jamanetwork.com/article.aspx?doi=10.1001/jamaneurol.2014.2819. JAMA Neurology…

JAMANEU_OF:10062014

JAMANEU_OF:09292014

JAMANEU_OF:09222014

Statins Associated With Better Outcomes in Hospitalization for Brain Hemorrhage

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, SEPTEMBER 22, 2014 Media Advisory: To contact author Alexander C. Flint, M.D., Ph.D., call Janet Byron at 510-891-3115 or email Janet.L.Byron@kp.org. To contact editorial corresponding author Randolph S. Marshall, M.D., call Karin Eskenazi at 212-342-0508 or email ket2116@cumc.columbia.edu. To place an electronic embedded link to this study in your…

JAMANEU_OF:09152014

JAMANEU_OF:09082014

JAMANEU:09082014

Study Examines Immunosuppressant Effect on Central Nervous System Disorder

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, SEPTEMBER 8, 2014 Media Advisory: To contact corresponding author Ho Jin Kim, M.D., Ph.D., email hojinkim@ncc.re.kr. To contact editorial author Bruce Cree, M.D., Ph.D., call Pete Farley at 415-502-4608 or email peter.farley@ucsf.edu. To place an electronic embedded link to this study in your story Links for this study and…

JAMANEU_OF:09012014

JAMANEU_OF:08252014

Two Case Reports of Rare Stiff Person Syndrome

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, AUGUST 25, 2014 Media Advisory: To contact corresponding author Harold L. Atkins, M.D., call Paddy Moore at 613-737-8899 x73687 or email padmoore@ohri.ca. To place an electronic embedded link to this study in your story A link for this case report will be live at the embargo time: http://archneur.jamanetwork.com/article.aspx?doi=10.1001/jamaneurol.2014.1297. JAMA…

Complication Risk of Deep Brain Stimulation Similar for Older, Younger Parkinson Patients

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, AUGUST 25, 2014 Media Advisory: To contact corresponding author Shivanand P. Lad, M.D., Ph.D., call Sarah Avery at 919-660-1306 or email sarah.avery@duke.edu. An author podcast will be available when the embargo lifts on the JAMA Neurology website: http://bit.ly/LSa1MM. To place an electronic embedded link to this study in…

JAMANEU_OF:08182014

JAMANEU:08112014

JAMANEU_OF:08112014

Normal Cognition in Patient Without Apolipoprotein E, Risk Factor for Alzheimer

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, AUGUST 11, 2014 Media Advisory: To contact corresponding author Mary J. Malloy, M.D., call Laura Kurtzman at 415-476-3163 or email Laura.Kurtzman@ucsf.edu. To contact editorial author Joachim Herz, M.D., call Gregg Shields at 214-648-3404 or e-mail Gregg.shields@utsouthwestern.edu. To place an electronic embedded link to this study in your story Links…

JAMANEU_OF:08042014

Study Examines Midlife Hypertension, Cognitive Change Over 20-Year Period

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, AUGUST 4, 2014 Media Advisory: To contact author Rebecca F. Gottesman, M.D., Ph.D., call  Audrey Huang at 410-614-5105 or email audrey@jhmi.edu. To contact editorial author Philip B. Gorelick, M.D., M.P.H., call Jason Cody at 517- 432-0924 or email jason.cody@cabs.msu.edu. To place an electronic embedded link to this study…

JAMANEU_OF:07282014

JAMANEU_OF:07212014

Study Examines Blood Markers, Survival in Patients with ALS

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, JULY 21, 2014 Media Advisory: To contact author Adriano Chiò, M.D., email achio@usa.net. To place an electronic embedded link to this study in your story  Links for this study and editorial will be live at the embargo time: http://archneur.jamanetwork.com/article.aspx?doi=10.1001/jamaneurol.2014.1129. JAMA Neurology Bottom Line: The blood biomarkers serum albumin…

JAMANEU:07142014

JAMANEU_OF:07142014

Study Examines Dietary Fatty Acid Intake, Risk for Lou Gehrig Disease

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, JULY 14, 2014 Media Advisory: To contact author Kathryn C. Fitzgerald, M.Sc., call Todd Datz at 617-432-8413 or email tdatz@hsph.harvard.edu. To contact editorial author Michael Swash, M.D., email mswash@btinternet.com. To place an electronic embedded link to this study in your story  Links for this study and editorial will be live…

JAMANEUR_OF:07072014

JAMANEU_OF:06302014

JAMANEU_OF:06232014

Examining Lifetime Intellectual Enrichment and Cognitive Decline in Older Patients

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, JUNE 23, 2014 Media Advisory: To contact author Prashanthi Vemuri, Ph.D., call Duska Anastasijevic at 507-538-7003 or email anastasijevic.duska@mayo.edu.   JAMA Neurology   Bottom Line: Higher scores that gauged education (years of school completed) and occupation (based on attributes, complexities of a job), as well as higher levels…

JAMANEU_OF:06162014

Military Personnel with Concussive Traumatic Brain Injury Caused by Blast or Nonblast Event Had No Difference in Outcomes

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, JUNE 16, 2014 Media Advisory: To contact corresponding author David L. Brody, M.D., Ph.D., call Judy Martin at 314-286-0105 or email martinju@wustl.edu.   JAMA Neurology   Bottom Line: Military personnel with concussive traumatic brain injury (TBI) caused by a blast or a nonblast-related event had similar outcomes, including…

JAMANEU_OF:06092014

JAMANEU:06092014

JAMANEU_OF:06022014

No Sign of ‘Obesity Paradox’ in Obese Patients with Stroke

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, JUNE 2, 2014 Media Advisory: To contact corresponding author Tom S. Olsen, M.D., Ph.D., email tso@dadlnet.dk   JAMA Neurology   Bottom Line: Researchers found no evidence of an “obesity paradox” (some studies have suggested overweight or obese patients have lower mortality rates than underweight or normal weight patients)…

JAMANEU_OF:05262014

JAMANEU_OF:05192014

JAMANEU_OF:05122014

JAMANEU:05122014

Study Examines Association Between Small-Vessel Disease, Alzheimer Pathology

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, MAY 12, 2014 Media Advisory: To contact author Maartje I. Kester, M.D., Ph.D., email m.kester@vumc.nl. JAMA Neurology   Bottom Line: Cerebral small-vessel disease (SVD) and Alzheimer disease (AD) pathology appear to be associated. Author:  Maartje I. Kester, M.D., Ph.D., of the VU University Medical Center, Amsterdam, the Netherlands,…

JAMANEU_OF:05052014

JAMANEU_OF:04282014

JAMANEU_OF:04212014

JAMANEU_OF:04142014

JAMANEU_OF:04072014

Viewpoint Offers Details of BRAIN Initiative

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, APRIL 7, 2014 Media Advisory: To contact author Cornelia I. Bargmann, Ph.D., call Zach Veilleux at 212-327-8982 or email zveilleux@rockefeller.edu.   JAMA Neurology Viewpoint Highlight   JAMA Neurology is publishing online a Viewpoint written by Cornelia I. Bargmann, Ph.D., of Rockefeller University, New York, and William T. Newsome,…

JAMANEUR_OF:03312014

β-Amyloid Deposits Increase With Age, Associated With Artery Stiffness

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, MARCH 31, 2014 Media Advisory: To contact author Timothy M. Hughes, Ph.D., M.P.H., call Marguerite Beck at 336-716-4587 or email marbeck@wakehealth.edu. Please visit our For the Media website http://bit.ly/QbIRTK for a related editorial. JAMA Neurology Study Highlight   Bottom Line:  Stiffening of the arteries appears to be associated…

JAMANEUR_OF:03242014

Natalizumab Treatment in Patients with Multiple Sclerosis Associated with JC Virus Infection

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, MARCH 24, 2014 Media Advisory: To contact corresponding author Elliot M. Frohman, M.D., Ph.D., call Remekca Owens at 214-648-3404 or email remekca.owens@utsouthwestern.edu. An author podcast will be available when the embargo lifts at http://bit.ly/LSa1MM.   JAMA Neurology   Bottom Line:  Treatment with natalizumab in patients with multiple sclerosis…

JAMANEUR_OF:03172014

COPD Associated With Increased Risk for Mild Cognitive Impairment

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, MARCH 17, 2014 Media Advisory: To contact corresponding author Michelle M. Mielke, Ph.D., call Nick Hanson at 507-266-4945 or email hanson.nicholas@mayo.edu. JAMA Neurology     Bottom Line:  A diagnosis of chronic obstructive pulmonary disease (COPD) in older adults was associated with increased risk for mild cognitive impairment (MCI),…

JAMANEUR_ADHOC:03132014

Blood Biomarkers Could Help Guide Return to Play for Athletes After Concussion

EMBARGOED FOR RELEASE: 9 A.M. (CT), THURSDAY, MARCH 13, 2014 Media Advisory: To contact corresponding author Pastun Shahim, M.D., email pashtun.shahim@neuro.gu.se. To contact corresponding editorial author Ramon Diaz-Arrastia, M.D., Ph.D., call Gwendolyn Smalls at 301-295-3981 or email gwendolyn.smalls@usuhs.edu.   JAMA Neurology   Bottom Line: Ice hockey players in Sweden with a sports-related concussion had higher…

JAMANEUR_OF:03102014

JAMANEUR:03102014

JAMANEUR_OF:03032014

Study Examines Blood Test to Screen for Fatal Variant Creutzfeldt-Jakob Disease

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, MARCH 3, 2014 Media Advisory: To contact author Graham S. Jackson, Ph.D., email g.s.jackson@prion.ucl.ac.uk.   JAMA Neurology Study Highlights   Bottom Line: A blood test accurately screened for infection with the agent responsible for variant Creutzfeldt-Jakob disease (vCJD), a fatal neurological disease.   Author: Graham S. Jackson, Ph.D.,…

JAMANEUR_OF:02242014

JAMANEUR_OF:02172014

Intracranial Carotid Artery Atherosclerosis Associated with Increased Stroke Risk

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, FEBRUARY 17, 2014 Media Advisory: To contact corresponding author M. Arfan Ikram, M.D., Ph.D., email m.a.ikram@erasmusmc.nl. Please visit our For the Media site (http://media.jamanetwork.com) for a related editorial.     JAMA Neurology Study Highlights   Intracranial Carotid Artery Atherosclerosis Associated with Increased Stroke Risk   A build-up of…

JAMANEUR:02102014

JAMANEUR_OF:02102014

JAMANEUR_OF:02032014

Case Report on Genetic Diagnosis of Fatal Disorder in Embryos Before Pregnancy

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, February 3, 2014 Media Advisory: To contact corresponding author Ilan Tur-Kaspa, M.D., call 312-493-3068 or email iturkaspa@gmail.com or DrTK@infertilityIHR.com and for corresponding author Murali Doraiswamy, M.B.B.S., F.  R.C.P., call Rachel Harrison at 919-419-5069 or email rachel.harrison@duke.edu.   JAMA Neurology Study Highlights   Genetic testing of embryos for a…

JAMANEUR_OF:01272014

Byproduct of Pesticide DDT in Blood Associated with Increased Alzheimer Risk

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, JANUARY 27, 2014 Media Advisory: To contact author Jason R. Richardson, Ph.D., call Robin Lally at 848-932-0557 or email rlally@ucm.rutgers.edu. Please visit our For the Media website (http://media.jamanetwork.com/) for a related editorial.   JAMA Neurology Study Highlights   An increased risk for Alzheimer disease (AD) appears to be…

JAMANEUR_OF:01202014

Vitamin D Status Associated With Multiple Sclerosis Activity, Progression

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, JANUARY 20, 2014 Media Advisory: To contact author Alberto Ascherio, M.D., Dr.P.H., call Karen Feldscher at 617-432-8439 or email kfeldsch@hsph.harvard.edu.   JAMA Neurology Study Highlights   Vitamin D status appears to be associated with reduced disease activity in patients with multiple sclerosis (MS) and a slower rate of…

JAMANEUR_OF:01132014

JAMANEUR:01132014

JAMANEUR_OF:01062014

Inverse Association Between Alcohol Consumption, Multiple Sclerosis

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, JANUARY 6, 2013 Media Advisory: To contact author Anna Karin Hedstrӧm, M.D., email anna.hedstrom@ki.se.   JAMA Neurology Study Highlights   Drinking alcohol appears to have a dose-dependent inverse (opposite) association with the risk of developing multiple sclerosis (MS) and researchers suggest their findings give no support to advising…

JAMANEUR_OF:12302013

Hypothyroidism Not Associated With Mild Cognitive Impairment in Study

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, DECEMBER 30, 2013 Media Advisory: To contact author Ajay K. Parsaik, M.D., call Deborah M. Lake at 713-500-3030 or email Deborah.M.Lake@uth.tmc.edu. CHICAGO – Hypothyroidism was not associated with mild cognitive impairment (MCI) in a study of older patients, according to a report published by JAMA Neurology, a JAMA…

JAMANEUR_OF:12232013

Study Examines Inosine to Increase Urate Levels in Patients with Parkinson Disease

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, DECEMBER 23, 2013 Media Advisory: To contact corresponding author Michael A. Schwarzschild, M.D., Ph.D., call Mike Morrison at 617-724-6425 or email mdmorrison@partners.org. CHICAGO – The drug inosine appears to be a safe and effective way to raise blood and cerebrospinal fluid urate levels in patients with early Parkinson…

JAMANEUR_OF:12162013

JAMANEUR:12092013

JAMANEUR_OF:12092013

JAMANEUR_OF:12022013

JAMANEUR_OF:11252013

JAMANEUR_OF:11182013

JAMANEU_OF:11112013

Study Examines Amyloid Deposition in Patients with Traumatic Brain Injury

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, NOVEMBER 11, 2013 Media Advisory: To contact corresponding author David K. Menon, Ph.D., FMedSci, email dkm13@wbic.cam.ac.uk.   JAMA Neurology Study Highlights   Patients with traumatic brain injury (TBI) had increased deposits of β-Amyloid (Αβ) plaques, a hallmark of Alzheimer Disease (AD), in some areas of their brains in…

JAMANEUR_OF:11042013

JAMANEUR_OF:10282013

JAMANEUR_OF:10212013

Less Sleep Associated with Brain Imaging Findings of Alzheimer Disease in Elderly

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, OCTOBER 21, 2013 Media Advisory: To contact author Adam P. Spira. Ph.D., call Natalie Wood-Wright at 410-614-6029 or email nwoodwri@jhsph.edu.   CHICAGO – Getting less sleep and poor sleep quality are associated with abnormal brain imaging findings suggesting Alzheimer disease (AD) in older adults, according to a report…

JAMANEUR_OF:10142013

JAMANEUR:10142013

JAMANEUR_OF:10072013

JAMANEUR_OF:09302013

JAMANEUR_OF:09232013

Prenatal Exposure to Antiepileptic Drugs Associated With Impaired Fine Motor Skills at Age 6 Months; No Harmful Effects of Breastfeeding

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, SEPTEMBER 23, 2013 Media Advisory: To contact author Gyri Veiby, M.D., email gyri.veiby@hotmail.com. To contact editorial author Paul C. Van Ness, M.D., call Remekca Owens at 214-648-3404 or email remekca.owens@utsouthwestern.edu. CHICAGO – Prenatal exposure to antiepileptic medications was associated with an increased risk of impaired fine motor skills…

JAMANEUR_OF:09162013

Study Examines Parkinsonism in 1 County in Minnesota

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, SEPTEMBER 16, 2013 Media Advisory: To contact corresponding author Walter A. Rocca, M.D., M.P.H., call Nick Hanson at 507-284-5005 or email Hanson.Nicholas@mayo.edu.   JAMA Neurology Study Highlights   Study Examines Parkinsonism in 1 County in Minnesota   Walter A. Rocca, M.D., M.P.H., of the Mayo Clinic, Rochester, Minn.,…