Original Investigation

Early Enteral vs Oral Postoperative Nutrition After Pancreatoduodenectomy

JAMA Surgery 10.1001/jamasurg.2026.1048

April 22, 2026 at 11:00 AM EDT

Read the full article

Does early supplemental enteral nutrition after pancreatoduodenectomy improve postoperative morbidity compared with oral nutrition?In this randomized clinical trial that included 144 patients, patients with early supplemental enteral nutrition had a statistically significant lower mean comprehensive complication index (25.5) than patients with oral nutrition (35.8).In malnourished patients, use of early supplemental enteral nutrition should be routinely considered, as its global impact could be significant considering the high morbidity rates after pancreatoduodenectomy.

Corresponding Author: Gaëtan-Romain Joliat, MD, PhD, Department of Visceral Surgery, Lausanne University Hospital CHUV, Rue du Bugnon 46, 1011 Lausanne, Switzerland (gaetan-romain.joliat@chuv.ch).

Link to the article in your story

We encourage you to link out to this article in your story using the link below. It includes an access token that will give free access to the article for your readers up to one year after publication. (The link will be live after the article publishes and embargo is lifted.)

https://jamanetwork.com/journals/jamasurgery/fullarticle/10.1001/jamasurg.2026.1048?utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_term=042226

Please see the article for additional information, including full author list, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

Need more information? Contact us.

Editor's Picks