Viewpoint

Overmystifying the Psychedelic Experience

JAMA Psychiatry 10.1001/jamapsychiatry.2025.3032

October 29, 2025 at 11:00 AM EDT

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This Viewpoint addresses the dual domains of psychedelic experience—neurobiological changes and subjective experience—and argues for rigorous investigation of both domains.

Corresponding Author: Jack D. C. Dahan, BSc, MA, Amsterdam University Medical Centers, Meibergdreef 9, 1105 AZ Amsterdam, the Netherlands (j.d.dahan@amsterdamumc.nl).

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