Cannabis Use Among Individuals With Psychosis After State-Level Commercial Cannabis Legalization

How does legalizing adult-use cannabis affect use patterns among individuals with psychosis?In this cohort study of 7465 responses from 1856 adults in the US, difference-in-differences analyses found that 30-day cannabis use increased by 9.53 percentage points after legalization among individuals with psychosis.Results of this study suggest that cannabis use sharply increased after recreational cannabis legalization among individuals with psychosis by a greater amount than in the general population, and policymakers, scientists, clinicians, and regulators should collaborate to minimize potential harms to this vulnerable subpopulation.

Corresponding Author: Andrew S. Hyatt, MD, Health Evaluation Research Lab, Cambridge Health Alliance, Department of Psychiatry, Harvard Medical School, 1035 Cambridge St, #23, Cambridge, MA 02411 (ashyatt@challiance.org).

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