Research Letter

Out-of-Pocket Cost of Spinal Muscular Atrophy Gene Therapies Among Commercially Insured Patients

JAMA Pediatrics 10.1001/jamapediatrics.2026.0641

April 13, 2026 at 11:00 AM EDT

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This cross-sectional study evaluates insurance and patient spending for the spinal muscular atrophy medications nusinersen, onasemnogene abeparvovec-xioi, and risdiplam from 2021 through 2022.

Corresponding Author: Mariana P. Socal, MD, PhD, Department of Health Policy and Management, Johns Hopkins Bloomberg School of Public Health, 615 N Wolfe St, Ste W7503D, Baltimore, MD 21205 (socal@jhu.edu).

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