Long-Term Cardiometabolic Outcomes in Children With Metabolically Healthy and Unhealthy Obesity

Do children with metabolically healthy obesity (MHO) have an increased risk in long-term cardiometabolic outcomes?A cohort of 7275 children with obesity and 35 636 general population comparators found that, by age 30 years, those with MHO had significantly higher cumulative incidences of type 2 diabetes, hypertension, and dyslipidemia compared with the general population. Weight loss was associated with lower risk of cardiometabolic outcomes.Results suggest that children with MHO have an increased associated risk of cardiometabolic diseases up to young adulthood; pediatric obesity treatment should be offered regardless of metabolic status.

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