Viewpoint

Youth Suicide and the Evidence Paradox

JAMA Pediatrics 10.1001/jamapediatrics.2026.0275

April 06, 2026 at 11:00 AM EDT

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This Viewpoint discusses youth suicide rates in the US and how an evidence paradox—the populations at greatest risk are those in which randomized clinical trials are the most difficult to conduct—has affected prevention efforts.

Corresponding Author: Nilson N. Mendes Neto, MD, Harvard Medical School, 25 Shattuck St, Boston, MA 02115 (nilsonnogueiramendesneto@hms.harvard.edu).

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