Review

Naloxone and Buprenorphine Treatment for Adolescent Opioid Overdose and Opioid Use Disorder

JAMA Pediatrics 10.1001/jamapediatrics.2025.6113

February 09, 2026 at 11:00 AM EST

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This narrative review summarizes literature on opioid use, overdose, and misuse among adolescents as well as the use of naloxone and buprenorphine in adolescent opioid treatment.

Corresponding Author: Alexis Ball, MD, MPP, Department of Pediatrics, School of Medicine, University of Washington and Seattle Children’s Research Institute, M/S CURE-3 PO Box 5371, Seattle, WA 98145-5005 (aball775@uw.edu).

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