Review

Head and Neck Cancer Salvage Surgery in the Era of Immunotherapy and Beyond

JAMA Otolaryngology–Head & Neck Surgery 10.1001/jamaoto.2025.3204

October 02, 2025 at 11:00 AM EDT

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Advances in immunotherapy and the development of future clinical trials incorporating immunotherapy in the HNSCC salvage setting have the potential to enhance patient selection and optimize surgical outcomes.

Corresponding Author: Nabil F. Saba, MD, Department of Hematology and Medical Oncology, Winship Cancer Institute, Emory University, Atlanta, GA 30322 (nfsaba@emory.edu).

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