Original Investigation

Patients With Head and Neck Cancer and High Health Care Costs

JAMA Otolaryngology–Head & Neck Surgery 10.1001/jamaoto.2025.1976

July 17, 2025 at 11:00 AM EDT

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What are the main predictors for high health care costs among patients with head and neck cancer?In this population-based cohort study, advanced cancer stage and receiving multiple treatment modalities were the strongest predictors of high health care costs. Female sex, older age, and lower socioeconomic status were associated with an increased likelihood for high health care costs, although with a weaker effect size.Future research should focus on evaluating screening strategies and early diagnosis to assess their potential effects on cost reduction and improved outcomes for patients with head and neck cancer.

Corresponding Author: Noémie Villemure-Poliquin, MD, MSc, Department of Otolaryngology–Head and Neck Surgery, University of Toronto, 27 King’s College Cir, Toronto, ON M5S 1A1, Canada (noemie.villemurepoliquin@mail.utoronto.ca).

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