Manual Marking Guidance vs Digital Guidance System–Assisted Capsulorhexis in Phacoemulsification
JAMA Ophthalmology 10.1001/jamaophthalmol.2025.4448November 13, 2025 at 11:00 AM EST
Is manual marking–assisted capsulorhexis (MMAC) using a lens caliper (LC) noninferior to digital guidance–assisted capsulorhexis (DGAC) for the accuracy of capsulorhexis in phacoemulsification for age-related cataract?In this noninferiority randomized clinical trial of 156 participants, MMAC was found to be noninferior to DGAC in terms of the accuracy of capsulorhexis, postoperative best-corrected visual acuity, and intraocular lens stability.These findings support MMAC with an LC as a feasible auxiliary capsulorhexis technique, which does not require special equipment and is simple to operate and therefore might be appropriate if similar outcomes are obtained in other clinical practice settings.
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