Patient-Reported Importance of Functional Benefit in Geographic Atrophy

What is the perceived acceptability of intravitreal complement inhibitor (IVCI) therapy among patients with geographic atrophy (GA)?This cross-sectional study of 153 UK-based patients with GA, more than half found intravitreal injections for GA at least very acceptable, assuming treatment had vision functional benefits. Acceptability was influenced by participants’ belief that treatments would maintain vision longer compared with no treatment and confidence in their ability to regularly attend in-clinic injections.For participants in this survey, IVCI therapy for GA was acceptable, assuming treatment had vision functional benefits, but careful counseling seems warranted to ensure patients understand the treatment’s anatomical and functional benefits and limitations.

Corresponding Author: Christiana Dinah, BSc, MBBS, MRes, Ophthalmology Department, Central Middlesex Hospital, London North West University Healthcare National Health Service Trust, Acton Lane, London NW10 7NS, United Kingdom (christiana.dinah@nhs.net).

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