Lymph Node Dissection Guideline Adherence and Survival in Patients With T1N0M0 Lung Adenocarcinoma

Is guideline-adherent lymph node dissection associated with survival benefit among patients with cT1N0M0 lung adenocarcinoma?In this cohort study of 27 191 patients with cT1N0M0 lung adenocarcinoma from a multicenter clinical database, lymph node dissection adherent with the 3 + 1 or the 6-station standard was associated with survival benefit among patients with adenocarcinoma of high-grade or no lepidic pattern, but not with lepidic without high-grade pattern.These findings suggest that the survival impact of guideline-adherent lymph node dissection differed among patients with adenocarcinomas of different histologic pattern types.

Corresponding Authors: Fengwei Tan, MD, PhD (tanfengwei@cicams.ac.cn), and Jie He, MD, PhD (prof.hejie@gmail.com), Department of Thoracic Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 17 Panjiayuan Nanli, Chaoyang District, Beijing 100021, China.

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