Review

Emerging Artificial Intelligence Technologies for Risk Assessment and Management in Acute Myeloid Leukemia

JAMA Oncology 10.1001/jamaoncol.2025.3601

November 06, 2025 at 11:00 AM EST

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AI technologies hold potential to improve AML treatment through enhanced risk stratification, early detection capabilities, and individualized treatment optimization. The transition toward explainable AI models is essential to clinical readiness, with federated learning architectures resolving data scarcity concerns. Seamless integration requires harmonized data standards, robust regulatory frameworks, and equitable access to technology to fully realize the transformative potential of AI in improving outcomes for patients with AML globally.

Corresponding Author: Huasheng Liu, MD, PhD, Department of Hematology, The First Affiliated Hospital of Xi’an Jiaotong University, 277 W Yanta Rd, Xi’an, Shaanxi, PR China (lhs681995@126.com).

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