COVID-19 Vaccine Booster Uptake and Effectiveness Among US Adults With Cancer

How effective were additional doses of COVID-19 vaccines at preventing COVID-19 hospitalizations among persons with cancer from January 2022 to August 2023?In a retrospective cohort study among persons with cancer in the US, additional monovalent COVID-19 vaccines reduced COVID-19 hospitalizations by 29%, with a number needed to vaccinate of 166 in January to August 2022, and a bivalent COVID-19 vaccine reduced COVID-19 hospitalizations by 30%, with a number needed to vaccinate of 310 in September 2022 to August 2023.In both time periods, COVID-19 vaccination was associated with protection from severe COVID-19 among persons with cancer.

Corresponding Author: Jacek Skarbinski, MD, Department of Infectious Diseases, Oakland Medical Center, 3600 Broadway, Oakland, CA 94611 (jacek.skarbinski@kp.org).

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