Research Letter

Methodological Considerations for Quantile Aggregation in Alzheimer Disease Trials

JAMA Neurology 10.1001/jamaneurol.2026.1240

May 18, 2026 at 11:00 AM EDT

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This study evaluates the quantile-aggregation method using both simulated data and publicly available Alzheimer disease randomized trial data.

Corresponding Author: Sarah F. Ackley, Brown University School of Public Health, 121 S Main St, Providence, RI 02903 (sarah_ackley@brown.edu).

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