US Burden of Disorders Affecting the Nervous System

What is the US burden of disorders affecting the nervous system?This cross-sectional study of the Global Burden of Disease 2021 study data found that, among the US population of 332.7 million, disorders affecting nervous system health impacted 180.3 million US individuals and were the top cause of disability, with 16.6 million disability-adjusted life-years. Conditions with the greatest collective disability were stroke, Alzheimer disease and other dementias, diabetic neuropathy, and migraine.Given the high prevalence of disorders affecting the nervous system, the United States should prioritize efforts to combat these conditions with new prevention strategies, therapeutics, and focused rehabilitation.

Corresponding Author: John P. Ney, MD, MPH, Department of Neurology, Yale University, 15 York St, New Haven, CT 06510 (john.ney@yale.edu).

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