Original Investigation

Out-of-Hospital Cardiac Arrest Survival at Nighttime

JAMA Network Open 10.1001/jamanetworkopen.2026.9828

April 29, 2026 at 11:00 AM EDT

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Does out-of-hospital cardiac arrest resuscitation with nighttime prehospital response remain associated with low rates of survival using contemporary data?In this retrospective cohort study including 874 415 patients from a nationwide out-of-hospital cardiac registry from 2013 to 2024, patients with prehospital response at nighttime (11:00 to 6:59 ) had 15% lower adjusted odds of neurologically favorable survival and 14% lower adjusted odds of return of spontaneous circulation.These findings suggest that nighttime prehospital responses to patients with out-of-hospital cardiac arrest are associated with lower odds of survival than daytime responses, and further work should explore effective strategies to improve survival at night.

Corresponding Author: Joshua M. Kimbrell, BA, Albert Einstein College of Medicine, 1300 Morris Park Ave, Bronx, NY, 10461 (joshua.kimbrell@einsteinmed.edu).

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