Prostate Cancer Incidence, Mortality, and Survival in Switzerland

What were the trends in prostate cancer (PCa) incidence, mortality, and relative survival across age and prognostic groups from 1980 to 2021 in Switzerland?In this cohort study of 142 665 cases with PCa, incidence increased markedly from 2015 to 2021, particularly lower-risk PCa among men aged 50 to 79 years. Incidence of metastatic PCa increased from 2011 to 2021 following the release of recommendations against routine screening, while prognosis improved and mortality declined from 1980 to 2021.These findings suggest that overdiagnosis of low-risk PCa increased in Switzerland and that there is substantial potential for optimizing early detection of PCa.

Corresponding Author: Dominik Menges, MD, PhD, MPH, Epidemiology, Biostatistics and Prevention Institute, University of Zurich, Hirschengraben 84, 8001 Zurich, Switzerland (dominik.menges@uzh.ch).

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