Machine Learning Model to Predict Postmastectomy Breast Reconstruction Complications
JAMA Network Open 10.1001/jamanetworkopen.2026.7232April 15, 2026 at 11:00 AM EDT
Can a machine learning (ML) model trained with both structured data and curated information from clinical notes accurately predict major postoperative complications in patients undergoing postmastectomy breast reconstruction (PMBR)?This prognostic study including 411 patients found that a trained extreme gradient boosting model predicted major complications after PMBR with an area under the receiver operating characteristic curve of 0.83, area under the precision-recall curve of 0.62, and accuracy of 80.59%. Model performance was consistent across both autologous and implant reconstruction.These findings demonstrate the feasibility of using an ML model trained with combined structured and unstructured clinical data to support patient risk assessment and decision-making across implant and autologous reconstruction.
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