Trends and Disparities in the Use of Next-Generation Sequencing in Patients With Cancer in the United States

What are the trends and disparities in the use of next-generation sequencing testing among patients with advanced cancers in the US?In this cohort study of 63 294 patients with advanced or metastatic breast, prostate, colorectal, pancreatic, and lung cancers, many patients did not undergo tumor genomic testing. Patients with low socioeconomic status, Black or Hispanic patients, and those covered by Medicaid or Medicare experienced significantly longer time to testing in some of these cancers compared with their respective reference groups.These findings suggest disparities persist in genomic testing and underscore the need for interventions to ensure equitable access to precision oncology.

Corresponding Authors: Umang Swami, MD, MS (umang.swami@hci.utah.edu), and Neeraj Agarwal, MD (neeraj.agarwal@hci.utah.edu), Huntsman Cancer Institute, University of Utah, 2000 Circle of Hope Dr, suite 5510, Salt Lake City, UT 84112.

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