Original Investigation

Sequenced Care Pathway vs Pain Navigator Pathway for Veterans With Low Back Pain

JAMA Network Open 10.1001/jamanetworkopen.2026.4421

April 02, 2026 at 11:00 AM EDT

Read the full article

Is a sequenced care pathway superior to a pain navigation care pathway for improving pain interference and physical function outcomes for individuals seeking primary care for low back pain?In this cluster randomized clinical trial investigating the effectiveness of different nondrug care pathways in 1817 participants, the 3-month differences in improvements (sequenced care vs navigated care) in pain interference (−0.6 points) and physical function (0.6 points) were not statistically significant.This trial suggests no advantage of a sequenced care pathway vs a care pathway that navigates individuals with low back pain to commonly used nondrug treatments (eg, physical therapy, yoga, tai chi, chiropractic, or acupuncture).

Corresponding Author: Steven Z. George, PhD, Duke Clinical Research Institute, Department of Orthopaedic Surgery, 300 W Morgan St, Duke University, Durham, NC 27701 (steven.george@duke.edu).

Link to the article in your story

We encourage you to link out to this article in your story using the link below. It includes an access token that will give free access to the article for your readers up to one year after publication. (The link will be live after the article publishes and embargo is lifted.)

Please see the article for additional information, including full author list, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

Need more information? Contact us.

Editor's Picks