Research Letter

Sociodemographics and Attrition in Children With Osteosarcoma Enrolled in the AOST0331 Clinical Trial

JAMA Network Open 10.1001/jamanetworkopen.2026.3666

March 27, 2026 at 11:00 AM EDT

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This cohort study examines whether participant attrition differed from enrollment to randomization by sociodemographics among children with localized osteosarcoma enrolled in a randomized clinical trial with delayed randomization.

Corresponding Author: Daniel J. Zheng, MD, MHS, MSHP, Division of Oncology, Children’s Hospital of Philadelphia, 3500 Civic Center Blvd, Hub 2569, Philadelphia, PA 19104 (zhengd1@chop.edu).

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