Postprandial Glucose Level Decreases and Appetite in Adults Without Diabetes

Are postprandial glucose level decreases associated with appetite among free-living adults without diabetes?In this cohort study of 7650 meals from 895 participants, postprandial glucose level decreases in the 2- to 3-hour period after meals varied widely. Postprandial glucose level decreases were associated with greater postprandial hunger at 2 to 3 hours and 3 to 4 hours and with a shorter time to the initiation of the next food intake.Our findings support postprandial glucose level decrease as a potential biomarker to enhance understanding of appetite regulation and as a potential target for appetite and weight management.

Corresponding Authors: Rob M. van Dam, PhD, Department of Exercise and Nutrition Sciences, Milken Institute School of Public Health, The George Washington University, 950 New Hampshire Ave NW #2, Washington, DC 20052 (rvandam@gwu.edu); Falk Müller-Riemenschneider, PhD, Saw Swee Hock School of Public Health, National University of Singapore, 12 Science Dr 2, Singapore, Singapore 117549 (falk.m-r@nus.edu.sg).

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