Lung Cancer Diagnosis Rates in Early Detection Programs in the Mississippi Delta
JAMA Network Open 10.1001/jamanetworkopen.2026.3171April 13, 2026 at 11:00 AM EDT
What is the cumulative lung cancer diagnosis rate (LCDR) among patients enrolled in lung cancer screening (LCS) and incidental pulmonary nodule (IPN) programs in the Mississippi Delta?In this cohort study of 40 612 patients, cumulative LCDRs at 36 months were 3.8% and 4.3% in the LCS and IPN programs, respectively. The LCDR was similar to or exceeded the 3.97% reported in the National Lung Screening Trial after a median follow-up of 6.5 years.These findings suggest that LCS and IPN programs may have greater outcomes associated with LCDRs than projected from clinical trial data.
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