Surgical Outcomes After Risk-Reducing Mastectomy Among and Carriers
JAMA Network Open 10.1001/jamanetworkopen.2026.2574April 03, 2026 at 11:00 AM EDT
Is risk-reducing mastectomy a safe procedure for or carriers in terms of cancer risk and surgical complications?In this cohort study of 1208 women, breast cancer was diagnosed in 1 of 507 women undergoing risk-reducing mastectomy (incidence, 2 cases per 10 000 person-years) and 112 of 701 women not undergoing risk-reducing mastectomy (incidence, 162 cases per 10 000 person-years). Nineteen of 507 women (3.7%) experienced a major early postoperative complication.This study suggests that risk-reducing mastectomy for and carriers is safe.
Link to the article in your story
We encourage you to link out to this article in your story using the link below. It includes an access token that will give free access to the article for your readers up to one year after publication. (The link will be live after the article publishes and embargo is lifted.)
Please see the article for additional information, including full author list, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
Need more information? Contact us.