Early Nephrology Consultation and Acute Kidney Injury in Hospitalized Patients

Among inpatients at risk for severe acute kidney injury (AKI), does an early structured nephrology consultation, triggered by a machine-learning risk score, lead to smaller peak changes in serum creatinine (SCr)?In this randomized clinical trial of 180 patients at high risk for AKI, an early nephrology consultation triggered by a machine-learning model did not reduce the peak change in SCr. Consultation recommendations were less likely to be followed for patients in the early consultation arm compared with the usual care arm.The findings of this study suggest that early nephrology consultations do not prevent rises in peak SCr among hospitalized patients at risk for severe AKI.

Corresponding Author: Jay L. Koyner, MD, Section of Nephrology, University of Chicago, 5841 S Maryland Ave, Ste S-507, MC5100, Chicago, IL 60637 (jkoyner@bsd.uchicago.edu).

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