Original Investigation

Generalization of AI-Based Gestational Age Assessment Using Blind Sweep Ultrasonography

JAMA Network Open 10.1001/jamanetworkopen.2026.22484

July 09, 2026 at 11:00 AM EDT

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Can artificial intelligence (AI) models trained on blind sweep ultrasonography scans generalize to new clinical settings and perform as well as traditional sonographers on estimating gestational age?In this diagnostic study of 385 participants, the AI model effectively generalized to new clinical environments and institutions, achieving a mean absolute error of 4.2 days, which was noninferior to the clinical standard.This AI system demonstrated strong potential to expand access to diagnostic tasks such as gestational age estimation, particularly in low-resource settings, by enabling novice operators to perform accurate ultrasonography assessments.

Corresponding Authors: Angelica Willis, MS (angelicaw@google.com), and Daniel Golden, PhD (dangolden@google.com), Google Research, 2000 N Shoreline Blvd, Mountain View, CA 94043.

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