Original Investigation

Hospital-Based Psychosocial Case Management and Suicide Prevention in South Korea

JAMA Network Open 10.1001/jamanetworkopen.2026.20950

July 07, 2026 at 11:00 AM EDT

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Does hospital-based assertive case management (ACM) reduce suicidal thoughts and behaviors in high-risk outpatients with major depressive disorder (MDD)?In this randomized clinical trial including 314 participants, ACM achieved a significantly greater reduction in Columbia–Suicide Severity Rating Scale total scores compared with standard care at 6 months.These findings suggest that hospital-based psychosocial ACM effectively complemented care for high-risk outpatients with MDD, thereby providing evidence to scale national suicide prevention policies.

Corresponding Authors: Hwa-Young Lee, MD, PhD, Department of Psychiatry, Soonchunhyang University Cheonan Hospital, 31, Suncheonhyang 6-gil, Dongnam-gu, Cheonan 31151, Republic of Korea (leehway@gmail.com); Jong-Woo Paik, MD, PhD, Department of Psychiatry, Kyung Hee University College of Medicine, 23 Kyung-heedae-ro, Dongdaemun-gu, Seoul 02453, Republic of Korea (paikjw@khu.ac.kr).

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