Original Investigation

Transradial vs Transfemoral Access for Cerebral Angiography

JAMA Network Open 10.1001/jamanetworkopen.2026.1929

March 19, 2026 at 11:00 AM EDT

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Is transradial access (TRA) noninferior to transfemoral access (TFA) in efficacy and safety for diagnostic cerebral angiography?In this randomized clinical trial including 858 patients, the success rate for accuracy in diagnostic cerebral angiography was lower in the TRA group (91%) compared with the TFA group (96%) and did not meet the prespecified noninferiority margin.TRA was not noninferior to TFA for diagnostic cerebral angiography.

Corresponding Authors: Yuxiang Gu, MD, Department of Neurosurgery, Huashan Hospital, Fudan University, No. 12 Mid Wulumuqi Rd, Shanghai 200040, P.R. China (guyuxiang1972@126.com); and Dezhi Kang, MD, Department of Neurosurgery, The First Affiliated Hospital of Fujian Medical University, Fuzhou 350005, P.R. China (kdz99988@vip.sina.com).

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