Original Investigation

Group Interpersonal Psychotherapy for Depression in Perinatal Adolescents in Kenya

JAMA Network Open 10.1001/jamanetworkopen.2026.18255

June 16, 2026 at 11:00 AM EDT

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How effective is task-shifted group interpersonal psychotherapy (IPT-G) for depression management in Kenya, and how do full vs mini versions fare with perinatal adolescents?In this randomized clinical trial of 122 participants, both full and mini IPT-G significantly reduced depressive symptoms compared with treatment as usual within 1 week post intervention, with full IPT-G demonstrating greater reductions than mini IPT-G over time.These findings suggest that contextually adapted IPT-G, delivered via task-shifting, is an effective and scalable approach for reducing perinatal adolescent depression in low-resource settings.

Corresponding Author: Manasi Kumar, PhD, Institute for Excellence in Health Equity, Department of Population Health, New York University School of Medicine, 180 Madison Ave, 7th Floor, New York, NY 10016 (Manasi.Kumar@nyulangone.org).

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