Original Investigation

Incidence and Outcomes of Bloodstream Infection in Solid Organ Transplant Recipients

JAMA Network Open 10.1001/jamanetworkopen.2026.1467

March 17, 2026 at 11:00 AM EDT

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What are the incidence and outcomes of candidemia in solid organ transplant recipients (SOTRs)?In this cohort study of 10 249 SOTRs, candidemia occurred in 1.67% and was associated with a 30-day mortality rate of 39.3%. Mortality risk was higher in patients with fluconazole-susceptible candidemia and higher in those with fluconazole-resistant candidemia compared with SOTRs without candidemia.Results of this study suggest that, although uncommon, candidemia is associated with high mortality, highlighting the need for effective prevention measures.

Corresponding Author: Seyed M. Hosseini-Moghaddam, MD, MSc, MPH, University Health Network, University of Toronto, 9078-MaRS, 585 University Ave, Toronto, ON M5G 2N2, Canada (sasan.hosseini@uhn.ca).

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