Recent COVID-19 Vaccination and Risk of SARS-CoV-2 Transmission

How effective is COVID-19 vaccination in preventing transmission of SARS-CoV-2?In this cohort study of 362 primary case participants with SARS-CoV-2 infection and their 763 household contacts, 62% of household contacts were infected with SARS-CoV-2. Household contacts of primary case participants vaccinated 6 months or less before onset had nearly one-half the infection risk compared with contacts of unvaccinated primary case participants.These findings suggest that COVID-19 vaccination may have an indirect benefit of decreasing transmission and thus reducing overall exposure to SARS-CoV-2.

Corresponding Author: Sarah E. Smith-Jeffcoat, MPH, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, 1600 Clifton Rd NE, MS H24-9, Atlanta, GA 30333 (uyi7@cdc.gov).

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