Original Investigation

Clinical Decision Support for Chronic Kidney Disease in Primary Care

JAMA Network Open 10.1001/jamanetworkopen.2026.11112

May 08, 2026 at 11:00 AM EDT

Read the full article

Does a clinical decision support system (CDSS) improve chronic kidney disease management in a primary care system with high disease burden and limited resources?In this cluster randomized trial of 3390 patients with chronic kidney disease from 30 primary care centers in China, both the intervention and control groups demonstrated comparable improvements over 6 months, with no significant additional benefit from a CDSS.These findings suggest that in resource-limited primary care, targeted education and policy support may be more foundational, whereas a CDSS should focus on tiered interruptive alerts with feedback-driven adjustments.

Corresponding Authors: Li Yang, PhD, MD (li.yang@bjmu.edu.cn) and Jicheng Lv, MD (chenglv@263.net), Department of Nephrology, Peking University First Hospital, No. 8 Xishiku St, Beijing 100034, China.

Link to the article in your story

We encourage you to link out to this article in your story using the link below. It includes an access token that will give free access to the article for your readers up to one year after publication. (The link will be live after the article publishes and embargo is lifted.)

Please see the article for additional information, including full author list, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

Need more information? Contact us.

Editor's Picks