Research Letter

Package Insert Warnings and Liver Function Tests for CDK4/6 Inhibitors for Breast Cancer

JAMA Network Open 10.1001/jamanetworkopen.2026.0787

March 05, 2026 at 11:00 AM EST

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This cohort study examines the utilization and timing of liver function tests among patients with breast cancer treated with cyclin-dependent kinase 4/6 inhibitors as recommended by the Food and Drug Administration insert warnings for these drugs.

Corresponding Author: Daniel C. Beachler, PhD, Staff VP, Safety daniel.beachler@carelon.com).

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