Extraintestinal Invasive Infections in the US

What are the incidences, antibiotic susceptibilities, and O serotypes of extraintestinal invasive infections in US communities?In this cohort study using population-based data from more than 7.2 million people, there were 1345 invasive infections; incidence rates were higher among older compared with younger populations and most frequently associated with infections of the urinary tract. Nearly 14% of infections were caused by extended-spectrum β-lactamase–producing , and O25B was the most prevalent O serotype.These findings suggest there is a significant burden of invasive infections in US communities, and high rates of antimicrobial resistance in this pathogen warrant continued prevention efforts.

Corresponding Author: Heather N. Grome, MD, MPH, Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention, 1600 Clifton Rd NE, MS H16-3, Atlanta, GA 30329-4027 (qds9@cdc.gov).

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