Acupuncture for Migraine Without Aura and Connection-Based Efficacy Prediction

Is acupuncture effective for migraine without aura, and can its efficacy be predicted from brain connectome data using machine learning?In this randomized clinical trial involving 120 participants with migraine without aura, acupuncture was effective in pain relief and functional improvement, and whole-brain resting-state functional connectivity can predict treatment outcomes.The findings highlight changes in brain functional connectivity during acupuncture, showing the brain connectome’s potential for personalized therapy.

Corresponding Author: Lu Liu, PhD, Department of Acupuncture and Moxibustion, Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing Key Laboratory of Acupuncture Neuromodulation, No. 23 Meishuguan Houjie, Beijing 100010, P.R. China (lululalavictor1985@126.com).

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