Generative AI Use and Depressive Symptoms Among US Adults

Are greater levels of generative artificial intelligence (AI) use by US adults associated with greater levels of depressive symptoms?In this survey study of 20 847 US adults, 10.3% reported daily use of generative AI, including 5.3% who used it multiple times per day. Greater levels of AI use were associated with modest increases in depressive symptoms, with odds of at least moderate depression 30% greater among those with daily use, particularly among younger users.These findings suggest there is a need to understand the nature and mechanism of this association and its heterogeneity across age-defined subgroups.

Corresponding Author: Roy H. Perlis, MD, MSc, Massachusetts General Hospital, 185 Cambridge St, 6th Floor, Boston, MA 02114 (rperlis@mgb.org).

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